NCT06969495 (DERMAL-LR) is a NA clinical trial of xLr oral gel in Mouth Ulcer, sponsored by Mahsa University.

Who is sponsoring NCT06969495?

NCT06969495 is sponsored by Mahsa University.

What drugs are being tested in NCT06969495?

Interventions in NCT06969495: xLr oral gel, Placebo, Kanolone.

What condition does NCT06969495 study?

NCT06969495 studies Mouth Ulcer.

Is NCT06969495 still recruiting?

NCT06969495 is currently completed. Last updated 15 May 2025.

Last reviewed 2025-05-15 · How we verify

NCT06969495: DERMAL-LR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pilot Clinical Study Testing Tiger Milk Mushroom Gel (Lignosus Rhinocerus TM02®) for Treating Mouth Ulcers

Completed NA Last updated 15 May 2025

What this trial tests

NA trial testing xLr oral gel in Mouth Ulcer in 21 participants. Completed in 23 February 2024.

Timeline

1 February 2023

Primary endpoint
30 November 2023

23 February 2024

Quick facts

Lead sponsor	Mahsa University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	21
Start date	1 February 2023
Primary completion	30 November 2023
Estimated completion	23 February 2024
Sites	1 location across Malaysia

Drugs / interventions tested

xLr oral gel
Placebo
Kanolone — full drug profile →

Conditions studied

Mouth Ulcer — all drugs for Mouth Ulcer →

Sponsor

Mahsa University

Who can join

Adults 20 to 50, any sex, with Mouth Ulcer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a pilot clinical trial study to investigate the wound healing capability of a TM02® water extract formulation in patient with minor oral ulcers (2 - 5 mm in size). The sclerotium of L. rhinocerus is traditionally used as a health tonic or treatment regime for asthma, bronchitis, various cancer ailments as well as discomforts caused by fright, fever, cough, vomiting, and injury. Further on to that, this mushroom has also been traditionally used by the local Malay and Chinese communities to treat wounds, although it is yet to be scientifically validated. Its sclerotia are being consumed in the form of decoction, in a betel quid, and other preparation method where the sclerotium is pounded with raw rice, infused, and subsequently taken as a drink. There is also a practice of biting/chewing of the sclerotium by local indigenous communities during their journeys in the wild.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Mahsa University trials

Trials by the same sponsor.

NCT07394634 — Efficiency of Self Extracted Tooth Graft in Extraction Socket : A Clinical and Radiographic Study · NA · enrolling by invitation
NCT04032548 — Effectiveness of Propolis Mouthwash on Gingivitis · NA · completed
NCT04076098 — Locally Delivered Minocycline in Advanced Periodontitis · Phase 4 · completed
NCT04042389 — Oral Hygiene Reminders in Orthodontic Patients · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06969495 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mahsa University
Last refreshed: 15 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06969495.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing