Last reviewed · How we verify
NCT06968715: HYDRO-RESPOND
Hydrogen-Rich Water and Metabolic Health in Adults: A 12-Week Randomized Trial
NA trial testing Experimental 1: low-breath hydrogen in Metabolic Syndrome in 40 participants. Completed in 30 November 2025.
30 October 2025
Quick facts
| Lead sponsor | University of Novi Sad, Faculty of Sport and Physical Education |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 40 |
| Start date | 1 April 2025 |
| Primary completion | 30 October 2025 |
| Estimated completion | 30 November 2025 |
| Sites | 1 location across Serbia |
Drugs / interventions tested
- Experimental 1: low-breath hydrogen
- Experimental 2: high-breath hydrogen
- Experimental 3: low-breath hydrogen
- Experimental 4: high-breath hydrogen
Conditions studied
- Metabolic Syndrome — all drugs for Metabolic Syndrome →
Sponsor
University of Novi Sad, Faculty of Sport and Physical Education
Who can join
Adults 30 to 65, any sex, with Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The HYDRO-RESPOND trial is a 12-week randomized controlled study investigating the effects of daily hydrogen-rich water (HRW) consumption on body composition and metabolic biomarkers in adults diagnosed with metabolic syndrome. The study also explores whether individual differences in baseline breath hydrogen levels influence response to HRW. Participants are randomly assigned to receive either HRW or a placebo, with outcomes including changes in body fat, waist circumference, glucose metabolism, lipid profiles, and inflammatory markers. The trial aims to determine the therapeutic potential of HRW and identify predictors of individual responsiveness.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06968715
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Novi Sad, Faculty of Sport and Physical Education trials
Trials by the same sponsor.
- NCT06859879 — A Combined Supplementation of Rosemary and Daylily for Enhancing Sleep Quality in Middle-Aged Adults · NA · completed
- NCT06788015 — Hydrogen-Infused Water for Endurance Performance, Body Hydration Biomarkers, and Health-Related Quality of Life · NA · completed
- NCT06660004 — Creatine HCl and Creatine Ethyl Ester Supplementation in Perimenopausal and Menopausal Women · NA · completed
- NCT06722326 — Hydrogen-rich Water and Appetite in Obesity · NA · completed
- NCT06371651 — Creatine and GAA for Brain Oxygenation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06968715 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Novi Sad, Faculty of Sport and Physical Education
- Last refreshed: 22 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06968715.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing