Last reviewed · How we verify
NCT06965335: HEBE
Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study
trial testing BIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC in Colo-rectal Cancer in 20 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Niguarda Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 17 April 2024 |
| Primary completion | 31 December 2026 |
| Estimated completion | 30 June 2027 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- BIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC — full drug profile →
Conditions studied
- Colo-rectal Cancer — all drugs for Colo-rectal Cancer →
Sponsor
Niguarda Hospital
Who can join
Adults 18 to 40, any sex, with Colo-rectal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06965335
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colo-rectal Cancer
Currently open trials in the same condition.
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- NCT07085169 — Low-dose Trifluridine/Tipiracil With Bevacizumab in mCRC · Phase 2 · recruiting
- NCT06880055 — Shield Post-Approval Study Protocol · recruiting
- NCT06905925 — The Effect of the Training Program Given to Permanent Colostomy Patients on Self-efficacy · NA · recruiting
Other Niguarda Hospital trials
Trials by the same sponsor.
- NCT05105399 — Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures · NA · not yet recruiting
- NCT07153224 — The MICROSCOPE Project · not yet recruiting
- NCT04763993 — Reflux Disease After Gastric Bypass Versus Sleeve Gastrectomy in Morbid Obese Patients: an Italian Study · NA · not yet recruiting
- NCT07432347 — Decoding Epigenetic Mechanisms Driving Immune Evasion in Liver Cancer With Omics Approaches · recruiting
- NCT07234409 — Clinical Trial Addressing the Best Surgical Approach for Partial Nephrectomy With Single Port Robotic System in the Mana · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06965335 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Niguarda Hospital
- Last refreshed: 11 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06965335.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing