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NCT06964425
Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study
NA trial testing Endoscopic retrograde cholangiopancreatography (ERCP) in Cholangiocarcinoma, Extrahepatic in 20 participants. Currently enrolling.
31 May 2025
Quick facts
| Lead sponsor | University Hospital Olomouc |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 20 |
| Start date | 4 February 2023 |
| Primary completion | 31 May 2025 |
| Estimated completion | 30 July 2025 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Endoscopic retrograde cholangiopancreatography (ERCP)
Conditions studied
- Cholangiocarcinoma, Extrahepatic — all drugs for Cholangiocarcinoma, Extrahepatic →
- Cholangiocarcinoma of the Extrahepatic Bile Duct — all drugs for Cholangiocarcinoma of the Extrahepatic Bile Duct →
- Cholangiocarcinoma, Perihilar — all drugs for Cholangiocarcinoma, Perihilar →
- Diagnosis — all drugs for Diagnosis →
Sponsor
University Hospital Olomouc
Who can join
18 and older, any sex, with Cholangiocarcinoma, Extrahepatic or Cholangiocarcinoma of the Extrahepatic Bile Duct. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06964425
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other University Hospital Olomouc trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06964425 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Olomouc
- Last refreshed: 2 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06964425.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing