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NCT06963944: IRIS-MAP
Physiological Dead Space and Intensive Care Mortality in Mechanically Ventilated Patients
trial in Invasive Mechanical Ventilation in 60 participants. Completed in 19 April 2025.
19 April 2025
Quick facts
| Lead sponsor | Karadeniz Technical University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 1 January 2024 |
| Primary completion | 19 April 2025 |
| Estimated completion | 19 April 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Invasive Mechanical Ventilation — all drugs for Invasive Mechanical Ventilation →
- Ventilation-Perfusion Mismatch — all drugs for Ventilation-Perfusion Mismatch →
- ICU Mortality — all drugs for ICU Mortality →
- Critical Illness — all drugs for Critical Illness →
Sponsor
Karadeniz Technical University
Who can join
18 and older, any sex, with Invasive Mechanical Ventilation or Ventilation-Perfusion Mismatch. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the relationship between physiological dead space and clinical outcomes, specifically mortality and discharge status, in adult patients receiving invasive mechanical ventilation in the intensive care unit (ICU). Physiological dead space refers to ventilated but non-perfused regions of the lungs and can be quantified using the Enghoff-modified Bohr equation based on capnographic and arterial CO₂ measurements. While volumetric capnography is a valuable tool in anesthesiology and perioperative care, its use in ICU settings remains limited. By continuously monitoring physiological dead space at the bedside, this study aims to provide real-time insight into ventilation-perfusion mismatch and assess its prognostic significance in critically ill patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06963944
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Invasive Mechanical Ventilation
Currently open trials in the same condition.
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Other Karadeniz Technical University trials
Trials by the same sponsor.
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- NCT07297498 — The Effect of Simulation-based Education Within the Framework of the Clinical Judgment Model on Nursing Students' Clinic · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06963944 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karadeniz Technical University
- Last refreshed: 9 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06963944.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing