Last reviewed · How we verify
NCT06962683
Post-surgery Muscle Preservation and Pain Reduction Through Blood Flow Restriction Training in Orthopedic Spinal Surgery
NA trial testing Blood-Flow-Restriction Training in Muscle Atrophy in 50 participants. Completed in 1 January 2025.
1 November 2024
Quick facts
| Lead sponsor | University Hospital, Bonn |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 March 2022 |
| Primary completion | 1 November 2024 |
| Estimated completion | 1 January 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Blood-Flow-Restriction Training
- Sham-BFR
Conditions studied
- Muscle Atrophy — all drugs for Muscle Atrophy →
- Postoperative Pain — all drugs for Postoperative Pain →
- Spondylolisthesis — all drugs for Spondylolisthesis →
- Spondylodiskitis — all drugs for Spondylodiskitis →
Sponsor
University Hospital, Bonn
Who can join
Adults 18 to 100, any sex, with Muscle Atrophy or Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This project investigates the effects of the Blood-Flow-Restriction (BFR) training method on postoperative muscle atrophy and pain after spinal surgery. Two groups are formed for this purpose. The intervention group receives a everyday BFR training during the postoperative stay at an individually measured occlusion pressure of 60-80%. The control group performs sham-BFR training at a fixed occlusion pressure of 20mmHg. The examinations are carried out before and several times after the operation (longest follow-up: 6 months). Among other things, muscle mass, muscle strength, pain perception and quality of life are assessed using questionnaires.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06962683
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Muscle Atrophy
Currently open trials in the same condition.
- NCT06631053 — FIT Exercise in 30d of ULLS-induced Muscle Disuse · NA · recruiting
- NCT06253104 — Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure · recruiting
- NCT06238609 — Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome · NA · active not recruiting
- NCT05919940 — Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO ) · NA · recruiting
- NCT05627440 — A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure · NA · recruiting
Other University Hospital, Bonn trials
Trials by the same sponsor.
- NCT07291765 — Blood Flow Restriction Training in Acute Geriatric Rehabilitation: A Randomized Controlled Trial on Its Effects and Safe · NA · not yet recruiting
- NCT07324330 — Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity · NA · recruiting
- NCT07299591 — Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Hip I · recruiting
- NCT07299565 — Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Knee · recruiting
- NCT07043569 — Clinical-randomized Trial of the Effect of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06962683 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Bonn
- Last refreshed: 8 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06962683.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing