Who is sponsoring PROOF?

PROOF is sponsored by Sun Yat-sen University.

What condition does PROOF study?

PROOF studies Follicular Lymphoma Grade 3A.

What drugs are being tested in PROOF?

Interventions: Obinutuzumab, CHOP, Bendamustine.

What is the status of PROOF?

PROOF is currently NOT_YET_RECRUITING.

Last reviewed 2025-05-08 · How we verify

Obinutuzumab With CHOP Versus Obinutuzumab With Bendamustine in the Treatment of Newly Diagnosed Follicular Lymphoma Grade 3A (PROOF)

NCT06961500 PHASE2 NOT_YET_RECRUITING

This is a multicenter, phase 2, randomized trial to evaluate the efficacy and safety of obinutuzumab with CHOP versus obinutuzumab with bendamustine in treatment-naïve follicular lymphoma (Grade 3A) patients.

Details

Lead sponsor	Sun Yat-sen University
Phase	PHASE2
Status	NOT_YET_RECRUITING
Enrolment	133
Start date	Thu May 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Nov 01 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Follicular Lymphoma Grade 3A

Interventions

Obinutuzumab
CHOP
Bendamustine

Countries

China