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NCT06952179
Pericardial Histopathology and COVID-19 Seropositivity
trial in Inflammatory Response in 93 participants. Completed in 1 June 2024.
1 February 2024
Quick facts
| Lead sponsor | Samsun University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 93 |
| Start date | 1 February 2023 |
| Primary completion | 1 February 2024 |
| Estimated completion | 1 June 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Inflammatory Response — all drugs for Inflammatory Response →
- COVID-19 — all drugs for COVID-19 →
- Pericardial Disease — all drugs for Pericardial Disease →
Sponsor
Samsun University
Who can join
Adults 20 to 75, any sex, with Inflammatory Response or COVID-19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective study aims to investigate the association between pericardial histopathologic inflammation grades (acute, chronic, or absent) and COVID-19 seropositivity in adult patients undergoing first-time isolated coronary artery bypass grafting (CABG). Pericardial tissue samples were collected during surgery and evaluated histopathologically, while preoperative COVID-19 serological testing was performed. The primary outcome is to determine whether COVID-19 seropositivity is associated with the severity of pericardial inflammation. Patients with prior cardiac surgery, active COVID-19 infection, systemic inflammatory diseases, chronic immunosuppressive therapy, or malignancy were excluded from the study.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Histopathological Evaluation of the Pericardium in CABG Patients With and Without Prior SARS-CoV-2 Infection: A Prospective Observational Study.
Ereren E, Ağırbaş H, Karal İH, Koç Şahin S, et al · · 2025 · PMID 41466119 · DOI 10.12659/msm.950106
Verify or expand the search:
- PubMed search for NCT06952179
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Samsun University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06952179 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Samsun University
- Last refreshed: 30 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06952179.
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