NCT06948929 is a NA clinical trial of SCV09 in Alzheimer Disease, sponsored by Chinese University of Hong Kong.

Who is sponsoring NCT06948929?

NCT06948929 is sponsored by Chinese University of Hong Kong.

What drugs are being tested in NCT06948929?

Interventions in NCT06948929: SCV09.

What condition does NCT06948929 study?

NCT06948929 studies Alzheimer Disease.

Is NCT06948929 still recruiting?

NCT06948929 is currently recruiting now. Last updated 3 September 2025.

Last reviewed 2025-09-03 · How we verify

NCT06948929

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Synbiotic Formula (SCV09) in Alzheimer's Disease Patients

Recruiting now NA Last updated 3 September 2025

What this trial tests

NA trial testing SCV09 in Alzheimer Disease in 30 participants. Currently enrolling.

Timeline

15 May 2025

Primary endpoint
15 May 2026

15 December 2026

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	30
Start date	15 May 2025
Primary completion	15 May 2026
Estimated completion	15 December 2026
Sites	1 location across Hong Kong

Drugs / interventions tested

SCV09

Conditions studied

Alzheimer Disease — all drugs for Alzheimer Disease →

Sponsor

Chinese University of Hong Kong

Who can join

Adults 60 to 90, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In recent years, emerging studies have revealed the role of gut microbiota in human health and diseases, including AD and other neurodegenerative conditions5. Although the underlying mechanism is still largely unknown, successful therapies targeting the gut-brain axis may serve as indirect evidence of the possible linkage. This pilot, single-arm study aims to estimate the efficacy and assess the safety profile of the use of a new synbiotic formula (SCV09) in improving dementia-related behaviour in Alzheimer's disease patients, paving the way for a large-scale randomised controlled trial in the future.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Microbial SCFAs as epigenetic mediators: fine-tuning the gut-brain axis in neurodegenerative disorders.
Xu X, Cheng Y, Liu X, Ding W, et al · · 2026 · PMID 41798063 · DOI 10.1016/j.crmicr.2026.100574
The gut microbiota influences neurodegenerative diseases through the gut-brain axis: molecular mechanisms and effects on immune function.
Yang J, Song X, Yan S, Li Q, et al · · 2025 · PMID 41601624 · DOI 10.3389/fimmu.2025.1739329

Verify or expand the search:

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Other Chinese University of Hong Kong trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06948929 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
Last refreshed: 3 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06948929.

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