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NCT06948526
Evaluation of Moringa Oleifera Leaf Extract Versus Sodium Hypochlorite in Pulpectomy of Nonvital Primary Molars
NA trial testing Moringa Oleifera Leaf Extract in Nonvital Primary Molars in 50 participants. Not yet recruiting.
1 June 2026
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 June 2025 |
| Primary completion | 1 June 2026 |
| Estimated completion | 1 August 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Moringa Oleifera Leaf Extract — full drug profile →
- Sodium Hypochlorite 1% — full drug profile →
Conditions studied
- Nonvital Primary Molars — all drugs for Nonvital Primary Molars →
Sponsor
Cairo University
Who can join
Adults 3 to 7, any sex, with Nonvital Primary Molars. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial aims to compare the clinical and radiographic success of Moringa Oleifera leaf extract with Sodium Hypochlorite as intracanal irrigants in pulpectomy of nonvital primary molars in children aged 3-7 years. The study evaluates both clinical parameters (pain, swelling, mobility) and radiographic healing (periapical changes, root resorption) over 12 months.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The "Colors" of Moringa: Biotechnological Approaches.
Villegas-Vazquez EY, Padilla-Mendoza JR, Carrillo-Pérez MS, Gómez-Cansino R, et al · · 2025 · PMID 40805688 · DOI 10.3390/plants14152338
Verify or expand the search:
- PubMed search for NCT06948526
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Moringa Oleifera Leaf Extract
Trials testing the same drug.
- NCT06971055 — Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars · NA · not yet recruiting
Other Cairo University trials
Trials by the same sponsor.
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- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06948526 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 29 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06948526.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing