Last reviewed · How we verify
NCT06945094: FlashV
A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.
trial testing caIMR in Coronary Microvascular Dysfunction (CMD) in 508 participants. Not yet recruiting.
30 December 2027
Quick facts
| Lead sponsor | Ge Junbo |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 508 |
| Start date | 1 July 2025 |
| Primary completion | 30 December 2027 |
| Estimated completion | 30 December 2029 |
Drugs / interventions tested
- caIMR
Conditions studied
- Coronary Microvascular Dysfunction (CMD) — all drugs for Coronary Microvascular Dysfunction (CMD) →
- Stable Angina Pectoris — all drugs for Stable Angina Pectoris →
- Unstable Angina Pectoris — all drugs for Unstable Angina Pectoris →
- Myocardial Ischemia, Angina Pectoris — all drugs for Myocardial Ischemia, Angina Pectoris →
Sponsor
Ge Junbo — full company profile →
Who can join
Adults 18 to 80, any sex, with Coronary Microvascular Dysfunction (CMD) or Stable Angina Pectoris. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The coronary angiography-derived index of microcirculatory resistance (caIMR) can be used to provide a binary assessment whether patients（with stable angina, unstable angina, suspected myocardial ischemia, or coronary artery stenosis of less than 50%, and without cardiomyopathy or obstructive epicardial coronary artery disease） have microcirculatory dysfunction, using a cutoff value of 25. This study aims to evaluate the binary classification performance of caIMR in two specific groups of patients: (1) those with caIMR values between 20 and 30, and (2) those with diffuse disease. We will do this by looking at differences in their Seattle Angina Questionnaire (SAQ) scores and their health outcomes over a three-year period.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06945094
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of caIMR
Trials testing the same drug.
- NCT06698432 — SHR Predicts CMD in Patients with CCS · completed
- NCT06190704 — Prognostic Significance of CMD Assessed by IMR in HCM Patients · completed
Other recruiting trials for Coronary Microvascular Dysfunction (CMD)
Currently open trials in the same condition.
- NCT06681896 — Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility Study · NA · recruiting
- NCT06588244 — INOCA-NA a Local Prospective Registry · recruiting
- NCT04674449 — iCorMicA - Stratified Medicine in Angina · NA · recruiting
- NCT06702748 — Prognostic Values of Coronary Microvascular Dysfunction Patients Treated with Rotational Atherectomy During Percutaneous · active not recruiting
Other Ge Junbo trials
Trials by the same sponsor.
- NCT05009667 — A Prospective, Multi-center Clinical Trial for Evaluating the Effectiveness and Safety of Online Coronary Angiography-De · completed
- NCT04571580 — Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06945094 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ge Junbo
- Last refreshed: 27 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06945094.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing