Who is sponsoring NCT06941584?

NCT06941584 is sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

What drugs are being tested in NCT06941584?

Interventions in NCT06941584: Test for AQP4, AChR, LGI1, and CASPR2 autoantibodies using cell-based assay, AIRE single gene sequencing, Molecular typing of HLA class I and II alleles.

What condition does NCT06941584 study?

NCT06941584 studies AIRE Deficiency.

Is NCT06941584 still recruiting?

NCT06941584 is currently recruiting now. Last updated 24 April 2025.

Last reviewed 2025-04-24 · How we verify

NCT06941584: NAD-AIRE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies

Recruiting now Last updated 24 April 2025

What this trial tests

trial testing Test for AQP4, AChR, LGI1, and CASPR2 autoantibodies using cell-based assay in AIRE Deficiency in 40 participants. Currently enrolling.

Timeline

6 November 2024

Primary endpoint
6 January 2027

6 January 2027

Quick facts

Lead sponsor	Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	40
Start date	6 November 2024
Primary completion	6 January 2027
Estimated completion	6 January 2027
Sites	1 location across Italy

Drugs / interventions tested

Test for AQP4, AChR, LGI1, and CASPR2 autoantibodies using cell-based assay
AIRE single gene sequencing
Molecular typing of HLA class I and II alleles

Conditions studied

AIRE Deficiency — all drugs for AIRE Deficiency →

Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Who can join

18 and older, any sex, with AIRE Deficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Studying genetic predisposition in autoimmune neurological diseases could help improve diagnostic accuracy and offer new treatment possibilities

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other Fondazione Policlinico Universitario Agostino Gemelli IRCCS trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06941584 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Last refreshed: 24 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06941584.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing