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NCT06940037: BRIO
The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults
NA trial testing Progressive Resistance Training in Aging in 300 participants. Currently enrolling.
31 August 2029
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 300 |
| Start date | 11 August 2025 |
| Primary completion | 31 August 2029 |
| Estimated completion | 31 August 2030 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Progressive Resistance Training
- Health Education
Conditions studied
- Aging — all drugs for Aging →
- Mobility Disability — all drugs for Mobility Disability →
Sponsor
Mayo Clinic
Who can join
65 and older, any sex, with Aging or Mobility Disability. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To critically examine biological, clinical, and behavioral modulators of progressive resistance training-associated exercise response heterogeneity in physical function and whole-body metabolism in older adults.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06940037
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06940037 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 16 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06940037.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing