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NCT06937502
Functionality and Clinical Correlates in TMD
trial in Temporomandibular Disorders (TMD) in 62 participants. Completed in 10 August 2025.
15 July 2025
Quick facts
| Lead sponsor | Istinye University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 62 |
| Start date | 10 June 2025 |
| Primary completion | 15 July 2025 |
| Estimated completion | 10 August 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Temporomandibular Disorders (TMD) — all drugs for Temporomandibular Disorders (TMD) →
- Functional Limitation — all drugs for Functional Limitation →
- Pain Severity — all drugs for Pain Severity →
- Neck Disability — all drugs for Neck Disability →
Sponsor
Istinye University
Who can join
Adults 18 to 55, any sex, with Temporomandibular Disorders (TMD) or Functional Limitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Temporomandibular disorders (TMD) are among the most common causes of orofacial pain and refer to structural and functional impairments related to the masticatory muscles, surrounding soft tissues, and/or the temporomandibular joint (TMJ). They negatively affect individuals physically, psychologically, and socially. The structural and functional impairments observed in TMD typically manifest as pain, restricted jaw movement, joint sounds, and muscle tension. In addition to these core symptoms, secondary issues such as chewing difficulties may also occur. Pain in TMD can negatively impact many orofacial functions, especially chewing. Functional impairment in individuals with TMD may result from pain, restricted jaw mobility, muscle tension, alterations in muscle activation, mandibular asymmetry, and morphological changes in the joint. These findings highlight the importance of addressing factors associated with functional impairment in individuals with TMD. Pain severity is strongly associated with functional limitations of the TMJ and neck disability. Particularly in cases of muscular-origin TMD, significant impairments in neck muscle function and joint mobility have been observed. This condition directly affects jaw function and leads to a decrease in quality of life. The impact of TMD on quality of life is directly related to pain severity and functional limitations. As pain severity increases, limitations in daily activities and reductions in overall quality of life also increase. Therefore, a multidisciplinary approach to TMD is essential for pain management, functional rehabilitation, and improving quality of life. The aim of this study is to investigate the relationships between functionality and pain, range of motion, neck disability, and quality of life in individuals with TMD. Understanding these relationships will form a basis for the effective management of TMD and improving individuals' quality of life.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06937502
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Temporomandibular Disorders (TMD)
Currently open trials in the same condition.
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- NCT07445516 — Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST) · recruiting
- NCT07373184 — Virtual Planning of Total Temporomandibular Joint Replacement · recruiting
- NCT06932406 — Orofacial Pain Self-management: Personality Moderation Effect · NA · recruiting
- NCT07075276 — Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement · NA · recruiting
Other Istinye University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06937502 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istinye University
- Last refreshed: 10 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06937502.
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