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NCT06935032
Functional Appliance Effects on Mandibular Soft Tissues
NA trial testing Twin block appliance in Mandibular Retrognathism in 46 participants. Completed in 24 July 2023.
28 June 2023
Quick facts
| Lead sponsor | Konya Necmettin Erbakan Üniversitesi |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 46 |
| Start date | 25 November 2021 |
| Primary completion | 28 June 2023 |
| Estimated completion | 24 July 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Twin block appliance
- Fixed orthodontic treatment
Conditions studied
- Mandibular Retrognathism — all drugs for Mandibular Retrognathism →
Sponsor
Konya Necmettin Erbakan Üniversitesi — full company profile →
Who can join
Adults 11 to 14, any sex, with Mandibular Retrognathism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aimed to evaluate the changes in mandibular and cervical soft tissues in Class II patients with mandibular retrognathia treated with the Twin Block appliance, compared to skeletal Class I patients without functional treatment, using profile photographs and cephalometric films. Sixteen patients with Class II Division 1, fifteen with Class II Division 2, and fifteen with skeletal Class I malocclusion were included. Measurements were performed at the beginning of treatment and after functional therapy. In the Class II Div 1 group, most parameters showed significant reductions, except for neck length and jaw tip contour. In the Class II Div 2 group, only the Sm-E plane measurement remained unchanged, while the control group showed minimal changes. Between-group comparisons indicated significant improvements in cervicomental angle, lip-jaw-throat angle, and other lower face soft tissue parameters, especially in Class II Division 1 patients. The findings suggest that Twin Block therapy effectively improves both skeletal and soft tissue profiles, with more pronounced soft tissue enhancement in Class II Division 1 cases.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06935032
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Twin block appliance
Trials testing the same drug.
- NCT04337086 — Effect of T4K Versus Twin Block in Developing Class II Division I Malocculsion · NA · completed
Other recruiting trials for Mandibular Retrognathism
Currently open trials in the same condition.
- NCT06651944 — Invisalign® System with Mandibular Advancement · NA · recruiting
Other Konya Necmettin Erbakan Üniversitesi trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06935032 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Konya Necmettin Erbakan Üniversitesi
- Last refreshed: 18 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06935032.
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