Who is sponsoring NCT06928480?

NCT06928480 is sponsored by Instituto de Investigación Sanitaria Aragón.

What condition does NCT06928480 study?

NCT06928480 studies Long Covid-19, Emotional Disorder, Anxiety, Depression Disorders, Emotion Regulation.

Is NCT06928480 still recruiting?

NCT06928480 is currently recruiting now. Last updated 22 May 2025.

Last reviewed 2025-05-22 · How we verify

NCT06928480: UP-LONGCOVID-R

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.

Recruiting now NA Last updated 22 May 2025

What this trial tests

NA trial testing Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Long Covid-19 in 90 participants. Currently enrolling.

Timeline

1 May 2025

Primary endpoint
31 December 2026

31 December 2026

Quick facts

Lead sponsor	Instituto de Investigación Sanitaria Aragón
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	90
Start date	1 May 2025
Primary completion	31 December 2026
Estimated completion	31 December 2026
Sites	2 locations across Spain

Drugs / interventions tested

Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders
Treatment as Usual (TAU) — full drug profile →

Conditions studied

Long Covid-19 — all drugs for Long Covid-19 →
Emotional Disorder — all drugs for Emotional Disorder →
Anxiety — all drugs for Anxiety →
Depression Disorders — all drugs for Depression Disorders →

Sponsor

Instituto de Investigación Sanitaria Aragón — full company profile →

Who can join

18 and older, any sex, with Long Covid-19 or Emotional Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults. Participants will be 90 adults (45 in the control group and 45 in the experimental group) with diagnosis of long COVID and comorbid emotional disorders. Participants will be recruited at Hospital Royo Villanova from Zaragoza, Spain. In this study it will be explored whether the changes obtained after the intervention in emotional disorders and cognitive complaints are maintained over 12 months. Additionally, levels of chronic stress will be longitudinally evaluated in the experimental group through accumulated cortisol levels in hair, before and after the application of the UP.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effectiveness and acceptability of the unified protocol for the transdiagnostic treatment of emotional disorders in people with long COVID-19: Study protocol for a randomized controlled trial.
Martínez-Borba V, Rodríguez-Márquez AE, Garcés-Arilla S, Peris-Baquero Ó, et al · · 2026 · PMID 41701690 · DOI 10.1371/journal.pone.0342908

Verify or expand the search:

Other recruiting trials for Long Covid-19

Currently open trials in the same condition.

NCT06586398 — A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID · NA · active not recruiting
NCT06305793 — RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG) · Phase 2 · active not recruiting
NCT06876948 — NENCA Study on Neurological Complications of Long COVID-19 in Children and Adolescents; Neurophysiological, Electroencep · NA · recruiting
NCT05379556 — LOng COvid COmorbidities: Andrological, Reproductive, Sexual Dysfunctions in Patients Recovered From COVID-19 · recruiting
NCT05293366 — LOng COvid COmorbidities: Endocrine,Metabolic,Neuropsychiatric,Muscle,Cardiovascular,Pulmonary,Dermatologic Dysfunctions · recruiting

Other Instituto de Investigación Sanitaria Aragón trials

Trials by the same sponsor.

NCT07070531 — Unified Protocol in Penitentiary Facilities · NA · not yet recruiting
NCT07185412 — Spanish Registry of Redo Procedures Following Pulmonary Vein Ablation by Pulsed Field Ablation Technology: RESET-PFA · not yet recruiting
NCT07321444 — Telerehabilitation in Shoulder Pathology · NA · completed
NCT06547450 — Unified Protocol for Treatment of Emotional Disorders in Brief Groups in Primary Care Services in Spain · NA · not yet recruiting
NCT07008365 — The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure · Phase 3 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06928480 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Instituto de Investigación Sanitaria Aragón
Last refreshed: 22 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06928480.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing