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NCT06925477
Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCT
NA trial testing DSLT treatment for Open-Angle Glaucoma in GLAUCOMA 1, OPEN ANGLE, D (Disorder) in 51 participants. Enrolling by invitation.
31 August 2026
Quick facts
| Lead sponsor | Medical University of South Carolina |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 51 |
| Start date | 7 August 2025 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 August 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- DSLT treatment for Open-Angle Glaucoma
- SLT treatment for Open-Angle Glaucoma
Conditions studied
- GLAUCOMA 1, OPEN ANGLE, D (Disorder) — all drugs for GLAUCOMA 1, OPEN ANGLE, D (Disorder) →
Sponsor
Medical University of South Carolina
Who can join
18 and older, any sex, with GLAUCOMA 1, OPEN ANGLE, D (Disorder). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study compares two laser treatments for open-angle glaucoma: Selective Laser Trabeculoplasty (SLT) and Direct Selective Laser Trabeculoplasty (DSLT). SLT is a widely used procedure that requires a manual technique with a goniolens, while DSLT is a new, automated, non-contact method using the Eagle system. The study will evaluate whether DSLT is as effective as SLT in reducing intraocular pressure (IOP). Participants will be randomly assigned to receive either treatment and will be monitored over 12 months to assess changes in IOP, medication use, and safety outcomes. The goal is to determine if the simpler DSLT procedure can provide similar results to SLT, potentially improving patient comfort and access to glaucoma care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06925477
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Currently open trials in the same condition.
- NCT07496957 — Preserflo MicroShunt Versus Trabeculectomy · NA · recruiting
Other Medical University of South Carolina trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06925477 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of South Carolina
- Last refreshed: 2 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06925477.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing