NCT06920849 (PRFperio) is a NA clinical trial of SRP+iPRF in Periodontal Disease, sponsored by Medical University of Bialystok.

Who is sponsoring NCT06920849?

NCT06920849 is sponsored by Medical University of Bialystok.

What drugs are being tested in NCT06920849?

Interventions in NCT06920849: SRP+iPRF, SRP.

What condition does NCT06920849 study?

NCT06920849 studies Periodontal Disease, Periodontitis.

Is NCT06920849 still recruiting?

NCT06920849 is currently active, enrolled. Last updated 10 April 2025.

Last reviewed 2025-04-10 · How we verify

NCT06920849: PRFperio

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Influence of PRF (Platelet-rich Fibrin) on the Clinical Parameters and the Concentration of Selected Inflammation Mediators in GCF (Gingival Crevice Fluid) of Patients With Periodontitis

Active, enrolled NA Last updated 10 April 2025

What this trial tests

NA trial testing SRP+iPRF in Periodontal Disease in 40 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

1 April 2022

Primary endpoint
30 June 2025

30 June 2025

Quick facts

Lead sponsor	Medical University of Bialystok
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	1 April 2022
Primary completion	30 June 2025
Estimated completion	30 June 2025
Sites	1 location across Poland

Drugs / interventions tested

SRP+iPRF — full drug profile →
SRP — full drug profile →

Conditions studied

Periodontal Disease — all drugs for Periodontal Disease →
Periodontitis — all drugs for Periodontitis →

Sponsor

Medical University of Bialystok

Who can join

18 and older, any sex, with Periodontal Disease or Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Assessment of the influence of injectable platelet-rich fibrin (i-PRF) on the clinical parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) in patients with periodontitis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Influence of Injectable Platelet-Rich Fibrin on the Clinical Parameters and the Levels of MMP-8 in the GCF in Non-Surgical Treatment of Periodontitis-Randomized Trial.
Skurska A, Chwiedosik M, Milewska AJ, Milewski R, et al · · 2025 · cited 1× · PMID 40558889 · DOI 10.3390/jfb16060202

Verify or expand the search:

Other recruiting trials for Periodontal Disease

Currently open trials in the same condition.

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NCT07257887 — Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Periodontitis · NA · recruiting
NCT07262606 — Salivary Mitofusin-1 Levels in Periodontitis: Associations With Disease Severity, Smoking, and Treatment Response · NA · recruiting

Other Medical University of Bialystok trials

Trials by the same sponsor.

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NCT07325552 — iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment · NA · recruiting
NCT07529145 — Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment · recruiting
NCT06855979 — The Impact of Dietary Intervention on Oxidative/antioxidant Markers and Gut Microbiota in Athletes · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06920849 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of Bialystok
Last refreshed: 10 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06920849.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing