Last reviewed · How we verify
NCT06918496: CLOSURE
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
NA trial testing Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair. in Aortic Aneurysm in 60 participants. Not yet recruiting.
31 March 2026
Quick facts
| Lead sponsor | Grena Biomed Limited |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 60 |
| Start date | 30 June 2025 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 March 2026 |
| Sites | 2 locations across Belgium, Poland |
Drugs / interventions tested
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
Conditions studied
- Aortic Aneurysm — all drugs for Aortic Aneurysm →
- Aortic Aneurysm Abdominal — all drugs for Aortic Aneurysm Abdominal →
- Valve Stenoses, Aortic — all drugs for Valve Stenoses, Aortic →
- Valve Regurgitation, Mitral — all drugs for Valve Regurgitation, Mitral →
Sponsor
Grena Biomed Limited
Who can join
18 and older, any sex, with Aortic Aneurysm or Aortic Aneurysm Abdominal. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a prosthetic or biologic graft, patch, or allograft. The effectiveness of the adhesive will be assessed after restoring blood flow.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06918496
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Aortic Aneurysm
Currently open trials in the same condition.
- NCT07438327 — AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation · recruiting
- NCT06998498 — Prehabilitation for Aortic Aneurysm Surgery: Proof-of-concept Trial · NA · recruiting
- NCT06549348 — Radiation Free Study · NA · recruiting
- NCT06834607 — Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms · NA · recruiting
- NCT06762561 — Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06918496 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Grena Biomed Limited
- Last refreshed: 9 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06918496.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing