Last reviewed · How we verify
NCT06912841: DBSMatchMaker
Deep Brain Stimulation (DBS) MatchMaker
trial in TOR1A in 500 participants. Enrolling by invitation.
1 December 2029
Quick facts
| Lead sponsor | Boston Children's Hospital |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 December 2024 |
| Primary completion | 1 December 2029 |
| Estimated completion | 1 December 2030 |
| Sites | 1 location across United States |
Conditions studied
- TOR1A — all drugs for TOR1A →
- PANK2 — all drugs for PANK2 →
- HPRT1 — all drugs for HPRT1 →
- EIF2AK2 — all drugs for EIF2AK2 →
Sponsor
Boston Children's Hospital
Who can join
Eligibility, any sex, with TOR1A or PANK2. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
DBS Matchmaker (https://www.dbsmatchmaker.com) is a platform designed to connect clinicians worldwide who are treating rare movement disorders with deep brain stimulation (DBS). It facilitates global collaboration and knowledge sharing to enhance patient care by improving patient selection, counseling, treatment, and outcomes for individuals with movement disorders.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Decoding GNAO1 mutations using <i>Caenorhabditis elegans</i> model system: past approaches and future prospectives.
Yadav S, Veliventi SS, Bhandari S, Gangurde S, et al · · 2025 · PMID 40771566 · DOI 10.3389/fncel.2025.1633744
Verify or expand the search:
- PubMed search for NCT06912841
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06912841 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Boston Children's Hospital
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06912841.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing