NCT06912308

Effect of Physiotherapy Methods on Functional and Respiratory Outcomes in ICU Patients With Respiratory Failure

Active, enrolled NA Last updated 9 April 2025

What this trial tests

NA trial testing Active Physiotherapy in Respiratory Insufficiency in 150 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

30 September 2023

Primary endpoint
30 September 2026

30 September 2027

Quick facts

Lead sponsor	Laura Rutkauskienė
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	health services research
Enrollment	150
Start date	30 September 2023
Primary completion	30 September 2026
Estimated completion	30 September 2027
Sites	1 location across Lithuania

Drugs / interventions tested

• Active Physiotherapy
• Passive Physiotherapy

Conditions studied

• Respiratory Insufficiency — all drugs for Respiratory Insufficiency →

Sponsor

Laura Rutkauskienė

Who can join

Adults 18 to 99, any sex, with Respiratory Insufficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the biomedical study is to assess the changes in functional and qualitative indicators of critically ill patients with respiratory failure by applying different physiotherapy methods. By conducting this study and developing the "Physiotherapy Protocol for Critically Ill Patients Treated in the ICU," physiotherapists worldwide could be encouraged to work using a unified and adapted method.

It is expected that the results, conclusions, and practical clinical recommendations derived from this study will be beneficial not only for rehabilitation specialists and intensivists in Lithuania but also for medical professionals working with respiratory diseases, including COVID-19 patients, at various stages of their treatment and consultation.

Implementing an appropriate physiotherapy procedure protocol is anticipated to bring economic benefits, as early physiotherapy is safe and can reduce the incidence of delirium, decrease the duration of patient sedation, shorten the number of days on mechanical ventilation, and minimize hospital stay duration. Additionally, it aims to restore or improve patients' functional and independence levels, help prevent ICU-acquired weakness, and can be easily implemented in intensive care units.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Early mobilization, breathing exercises and chest wall oscillation in patients with bilateral pneumonia disease in the intensive care unit: a randomized clinical trial.
   Rutkauskienė L, Kubilius R, Tamošuitis T. · · 2025 · cited 1× · PMID 41286729 · DOI 10.1186/s12890-025-04028-7