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NCT06910969: HORIZONS
Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease
NA trial testing HORIZONS Intervention in Bone Marrow Transplant Complications in 350 participants. Currently enrolling.
1 June 2029
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 350 |
| Start date | 13 August 2025 |
| Primary completion | 1 June 2029 |
| Estimated completion | 1 February 2030 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- HORIZONS Intervention
- Minimally enhanced usual care
Conditions studied
- Bone Marrow Transplant Complications — all drugs for Bone Marrow Transplant Complications →
- Graft-versus-Host Disease — all drugs for Graft-versus-Host Disease →
Sponsor
Massachusetts General Hospital
Who can join
18 and older, any sex, with Bone Marrow Transplant Complications or Graft-versus-Host Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and quality of life for hematopoietic stem cell transplant (HSCT) survivors living with chronic graft-versus host disease, and to identify critical facilitators and barriers for HORIZONS implementation and adoption.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06910969
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Bone Marrow Transplant Complications
Currently open trials in the same condition.
- NCT06590285 — Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation · NA · recruiting
- NCT06541002 — A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors · NA · recruiting
- NCT05709912 — Mobile CARE-App to Promote Coping for Caregivers of Patients Receiving Stem Cell Transplant · NA · active not recruiting
- NCT05629676 — Virtual Reality Intervention for Patients Undergoing BMT · NA · active not recruiting
- NCT03865589 — Using Ultrasound Elastography to Predict Development of Hepatic Sinusoidal Obstruction Syndrome · NA · active not recruiting
Other Massachusetts General Hospital trials
Trials by the same sponsor.
- NCT03585946 — Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis · withdrawn
- NCT07214831 — A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerg · NA · not yet recruiting
- NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
- NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
- NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06910969 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 3 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06910969.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing