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NCT06910332

The Effect of Shoulder Mobilization on Muscle Strength and Proprioception: a Randomized Double-blind Study

Completed NA Results posted Last updated 9 December 2025
What this trial tests

NA trial testing Joint mobilization in Healthy Male and Female Subjects in 48 participants. Completed in 30 June 2025.

Timeline
1 May 2025
Primary endpoint
30 June 2025
30 June 2025

Quick facts

Lead sponsorAcibadem University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposebasic science
Enrollment48
Start date1 May 2025
Primary completion30 June 2025
Estimated completion30 June 2025
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Acibadem University

Who can join

Adults 18 to 25, any sex, with Healthy Male and Female Subjects. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Proprioception Primary · Before the intervention

Laser pointer-assisted joint position reproduction test for shoulder: A laser pointer is strapped 5 cm above the lateral epicondyle. Participants actively move their arm to a predefined position (90° flexion or abduction), and the laser projection is marked. After lowering their arm and closing their eyes, they attempt to replicate the same position. The difference between the initial and reproduced positions (in millimeters) is measured

Proprioception Flexion
GroupValue95% CI
Mobilization Group54± 20.9
Sham Group62.8± 22.8
Proprioception Abduction
GroupValue95% CI
Mobilization Group86.7± 32.1
Sham Group85.3± 26.6
Proprioception Primary · Immediately after intervention

Laser pointer-assisted joint position reproduction test for shoulder: A laser pointer is strapped 5 cm above the lateral epicondyle. Participants actively move their arm to a predefined position (90° flexion or abduction), and the laser projection is marked. After lowering their arm and closing their eyes, they attempt to replicate the same position. The difference between the initial and reproduced positions (in millimeters) is measured

Proprioception Flexion
GroupValue95% CI
Mobilization Group52.3± 23.9
Sham Group52.2± 78.3
Proprioception Abduction
GroupValue95% CI
Mobilization Group91.2± 29
Sham Group78.3± 32.5
Muscle Strength Secondary · Before the intervention

Hand-held dynamometer (Lafayette) Muscle strength will be measured using a hand-held dynamometer (Lafayette). The assessment will focus on the shoulder flexors, abductors, internal rotators, and external rotators. Three measurements for each muscle group will be taken, and the average value will be recorded in kilograms (kg).

Shoulder Flexion
GroupValue95% CI
Mobilization Group17.3± 7.59
Sham Group19.5± 9.08
Shoulder Abduction
GroupValue95% CI
Mobilization Group17.6± 7.32
Sham Group17.8± 7.58
Shoulder External Rotation
GroupValue95% CI
Mobilization Group9.82± 3.60
Sham Group9.40± 4.10
Shoulder Internal Rotation
GroupValue95% CI
Mobilization Group15.4± 5.84
Sham Group14.6± 5.91
Muscle Strength Secondary · Immediately after intervention

Hand-held dynamometer (Lafayette) Muscle strength will be measured using a hand-held dynamometer (Lafayette). The assessment will focus on the shoulder flexors, abductors, internal rotators, and external rotators. Three measurements for each muscle group will be taken, and the average value will be recorded in kilograms (kg).

Shoulder Flexion
GroupValue95% CI
Mobilization Group18.3± 8.03
Sham Group18.5± 9.42
Shoulder Abduction
GroupValue95% CI
Mobilization Group16.6± 6.81
Sham Group16.5± 8.35
Shoulder External Rotation
GroupValue95% CI
Mobilization Group9.83± 3.05
Sham Group9.95± 4.87
Shoulder Internal Rotation
GroupValue95% CI
Mobilization Group15.1± 5.86
Sham Group14.2± 6.45

Sponsor's own description

This randomized, double-blind study examines the acute effects of shoulder mobilization on muscle strength and proprioception in healthy individuals. Forty-eight participants (aged 18-25) were randomly assigned to either a mobilization or sham intervention group. Muscle strength and proprioception were assessed before and after treatment. The mobilization group received passive shoulder joint glides, while the sham group underwent a placebo procedure. The study aims to determine whether mobilization affects strength and proprioception immediately.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Shoulder joint mobilization does not acutely affect strength or proprioception in healthy individuals.
    Acar AÖ, Amani A, Ishani S, Einollahi K, et al · · 2026 · PMID 41547871 · DOI 10.1038/s41598-025-34680-2

Verify or expand the search:

Other trials of Joint mobilization

Trials testing the same drug.

Other recruiting trials for Healthy Male and Female Subjects

Currently open trials in the same condition.

Other Acibadem University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06910332.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing