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NCT06908941
The Cardiovascular Benefits of Resistance Training and Dark Chocolate in Female Adults
NA trial testing dark chocolate in Vascular Function in Healthy Volunteers in 31 participants. Completed in 31 July 2024.
31 December 2023
Quick facts
| Lead sponsor | National Cheng Kung University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 31 |
| Start date | 1 September 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 July 2024 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- dark chocolate — full drug profile →
- milk chocolate
- high-intensity resistance exercise
Conditions studied
- Vascular Function in Healthy Volunteers — all drugs for Vascular Function in Healthy Volunteers →
Sponsor
National Cheng Kung University
Who can join
Adults 20 to 30, female only, with Vascular Function in Healthy Volunteers. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the effects of 85% dark chocolate supplementation on vascular function and nitric oxide (NO) levels during high-intensity resistance exercise in healthy women across menstrual phases. Using a randomized crossover design, 31 women consumed either dark chocolate or milk chocolate before exercising during the early follicular and mid-luteal phases. Vascular markers, including pulse wave velocity (ftPWV), arterial stiffness, blood pressure, and plasma NO levels, were measured at multiple time points.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Cardiovascular Benefits of Dark Chocolate Supplementation before High-Intensity Resistance Exercise in the Early Follicular and Mid-Luteal Phases of the Menstrual Cycle.
Wang CW, Fang SH, Yu TA, Chen LY, et al · · 2025 · PMID 40249472 · DOI 10.1186/s40798-025-00850-9
Verify or expand the search:
- PubMed search for NCT06908941
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of dark chocolate
Trials testing the same drug.
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Other recruiting trials for Vascular Function in Healthy Volunteers
Currently open trials in the same condition.
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Other National Cheng Kung University trials
Trials by the same sponsor.
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- NCT07509606 — Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease ( · NA · recruiting
- NCT06474130 — Assessing Cervical Sensorimotor Control With VR in Chronic Neck Pain · completed
- NCT06756113 — Digital Dyadic Empowerment Program on Lifestyle Modification for Chronic Kidney Disease Management · NA · completed
- NCT06542302 — The Effects of Cervical Sensorimotor Control Challenges on Gait Patterns, Cervical Sensorimotor Control During Dynamic T · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06908941 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cheng Kung University
- Last refreshed: 4 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06908941.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing