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NCT06907238

The Value of Novel Thrombus Markers in the Diagnosis and Treatment of Acute Pulmonary Embolism

Not yet recruiting Last updated 18 September 2025
What this trial tests

trial in Acute Pulmonary Embolism in 400 participants. Not yet recruiting.

Timeline
14 October 2025
Primary endpoint
30 July 2027
31 December 2027

Quick facts

Lead sponsorBeijing Anzhen Hospital
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment400
Start date14 October 2025
Primary completion30 July 2027
Estimated completion31 December 2027

Conditions studied

Sponsor

Beijing Anzhen Hospital

Who can join

Adults 18 to 120, any sex, with Acute Pulmonary Embolism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In response to the high mortality rate of patients with acute pulmonary embolism (APE) and the fact that only a small proportion of deceased patients can receive correct diagnosis, this study will use a sensitive, non-invasive, and feasible new thrombus molecular marker (TAT/PIC/TM/t-PAIC) to detect and evaluate the activation of the coagulation and fibrinolysis systems and endothelial system damage in patients, in order to monitor the early diagnosis and treatment of APE, reduce mortality, and improve patient quality of life. Therefore, this study intends to include 200 newly diagnosed APE patients to evaluate the sensitivity and specificity of the single and combined application of novel thrombus molecular markers for APE diagnosis; Detect the biomarker results of patients at different time points before and after treatment, and evaluate their value in APE treatment monitoring; Track and follow up on patients after discharge to explore the prognostic value of biomarkers for APE.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Acute Pulmonary Embolism

Currently open trials in the same condition.

Other Beijing Anzhen Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06907238.

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