Last reviewed · How we verify
NCT06904950: NDR
Nightmare Deconstruction and Reprocessing Pilot
NA trial testing Nightmare Deconstruction and Reprocessing in Nightmare in 11 participants. Completed in 30 November 2022.
31 July 2022
Quick facts
| Lead sponsor | Uniformed Services University of the Health Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | sequential |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 11 |
| Start date | 27 November 2019 |
| Primary completion | 31 July 2022 |
| Estimated completion | 30 November 2022 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Nightmare Deconstruction and Reprocessing
Conditions studied
- Nightmare — all drugs for Nightmare →
Sponsor
Uniformed Services University of the Health Sciences
Who can join
Adults 18 to 64, any sex, with Nightmare. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-arm, multisite (2 sites) pilot trial that is evaluating Nightmare Deconstruction and Reprocessing (NDR) for treating posttraumatic nightmares and insomnia in up to 30 military service members and veterans. Study aims are to test NDR's plausibility and tolerability and to test methodologic feasibility of collecting heart rate variability (HRV), electrodermal activity (EDA), and actigraphy data via a wristband device and peripheral blood samples within a pre-specified circadian window. Treatment consists of 8 sessions over 8 weeks. Participants are assessed at study visits 0, 1, and 7 and 1-month follow-up. Psychometric assessments include the Disturbing Dreams and Nightmare Severity Index, Pittsburgh Sleep Quality Index, and Clinician-Administered PTSD Scale for DSM-5.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06904950
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Nightmare
Currently open trials in the same condition.
- NCT06419959 — NightWare and Cardiovascular Health in Veterans With PTSD · NA · recruiting
- NCT06441864 — Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder · NA · recruiting
Other Uniformed Services University of the Health Sciences trials
Trials by the same sponsor.
- NCT07404787 — Evaluation of a Telehealth Case Management Intervention to Prevent Suicide Among Soldiers Discharged From Psychiatric Ho · NA · recruiting
- NCT07050238 — Evaluation of a Group-based, Skills Training for Increasing Mental Toughness · NA · recruiting
- NCT07286955 — Life Skills Training for Soldiers Arriving at Their First Duty Location · NA · recruiting
- NCT07121452 — Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System · NA · recruiting
- NCT07267819 — Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06904950 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Uniformed Services University of the Health Sciences
- Last refreshed: 1 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06904950.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing