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NCT06904118
Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel
NA trial testing Nano-reinforced Novel Hydrogen peroxide gel in Tooth Discoloration in 60 participants. Completed in 27 December 2023.
27 December 2023
Quick facts
| Lead sponsor | Pakistan Institute of Medical Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 13 June 2023 |
| Primary completion | 27 December 2023 |
| Estimated completion | 27 December 2023 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Nano-reinforced Novel Hydrogen peroxide gel — full drug profile →
- Conventional Hydrogen peroxide gel without nanoparicles — full drug profile →
Conditions studied
- Tooth Discoloration — all drugs for Tooth Discoloration →
- Tooth Sensitivity — all drugs for Tooth Sensitivity →
Sponsor
Pakistan Institute of Medical Sciences
Who can join
Adults 20 to 40, any sex, with Tooth Discoloration or Tooth Sensitivity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to learn the effect of Nano-fortified Bleaching on whitening and sensitivity of teeth.The main questions it aims to answer are: Does Nano-fortified Bleaching gel is more effective in enhancing the whitening in comparison to conventional bleaching gel ? Does Nano-fortified Bleaching gel is more effective in declining the sensitivity in comparison to conventional bleaching gel ? Participants will be divided into 2 groups i.e Group A where Nano-fortified Bleaching agent will be employed and Group B where Conventional Bleaching agent without nanoparticles will be used. One application of bleaching for thirty minutes will be carried out . Tooth sensitivity will be measured by VAS Scale having "No Pain" at one-end and "Worst Pain" at opposite-end .Color change will be measured with spectrophotometer.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06904118
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Tooth Discoloration
Currently open trials in the same condition.
- NCT06532526 — Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching. · NA · recruiting
- NCT06125132 — Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials. · NA · active not recruiting
- NCT04346849 — Tooth Discoloration Induced by Pulpotomy Materials · NA · active not recruiting
Other Pakistan Institute of Medical Sciences trials
Trials by the same sponsor.
- NCT07508202 — Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Bloc · Phase 4 · recruiting
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- NCT07456072 — Effectiveness of Chlorhexidine Impregnated Gauze Versus Povidone Iodine Dressing in Post Trauma Wound Care · NA · not yet recruiting
- NCT07319572 — Comparison of Chest Tube Wound Closure: Comparison Between Purse String Method and Plug Method. · NA · not yet recruiting
- NCT07300878 — Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics · Phase 4 · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06904118 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pakistan Institute of Medical Sciences
- Last refreshed: 1 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06904118.
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