NCT06903143

Piloting a Biomarker-augmented Alcohol Screening, Brief Intervention, and Referral to Treatment (SBIRT) Program Among HIV-affected Adolescents and Young Adults in Zambia

Not yet recruiting NA Last updated 13 June 2025

What this trial tests

NA trial testing Screening, brief intervention, and referral to treatment (SBIRT) in Alcohol in 60 participants. Not yet recruiting.

Timeline

1 August 2025

Primary endpoint
31 December 2025

30 April 2026

Quick facts

Lead sponsor	Centre for Infectious Disease Research in Zambia
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	60
Start date	1 August 2025
Primary completion	31 December 2025
Estimated completion	30 April 2026

Drugs / interventions tested

• Screening, brief intervention, and referral to treatment (SBIRT)

Conditions studied

• Alcohol — all drugs for Alcohol →

Sponsor

Centre for Infectious Disease Research in Zambia — full company profile →

Who can join

Adults 16 to 24, any sex, with Alcohol. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This will be a pilot study of an alcohol screening, brief intervention, and referral to treatment (SBIRT) program conducted within existing HIV prevention and treatment services for adolescents and young adults (AYA) in Lusaka, Zambia. The screening component of the program will feature both a self-report and a urine biomarker (ethyl glucuronide; EtG) to evaluate recent alcohol use. We will recruit 60 AYA to participate in the pilot. The specific aims of this pilot are to:

Specific aims:

1. Explore implementation factors of the SBIRT program within HIV prevention and treatment services through a process evaluation. We will quantitatively track the number of AYA in the SBIRT care cascade: 1) the number screened who have recent alcohol use; 2) the number of those with recent alcohol use who receive the brief intervention (BI); 3) the number of those who are referred for additional treatment; and 4) among those who are referred, the number who successfully link and complete treatment. We will collect time use data from clinic staff and counselors to estimate the time burden required for the SBIRT program. We will conduct 30 in-depth interviews with AYA three months after the screening. The sample will include adolescents who: (1) did not recently use alcohol; (2) received BI due to recent alcohol use that was low/moderate risk; and (3) were referred for treatment due to higher risk alcohol use. Interviews will focus on: (1) implementation factors (e.g., acceptability, feasibility) of the SBIRT program and (2) barriers and facilitators to the program's implementation. Focus group discussions and in-depth interviews will also be conducted with program staff (e.g., counselors, clinic staff) and other stakeholders (e.g., community leaders, policy-makers).
2. Evaluate the preliminary impact of the SBIRT program on AYA alcohol use. Among AYA who have recent alcohol use at screening, we will measure change in use at a three-month follow-up visit.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.