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NCT06899165
Psilocybin-Assisted Therapy for Intergenerational Trauma
Phase 2 trial testing Psilocybin in Psychological Stress in 100 participants. Currently enrolling.
31 May 2029
Quick facts
| Lead sponsor | Rachel Yehuda |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 28 August 2025 |
| Primary completion | 31 May 2029 |
| Estimated completion | 2 January 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Psilocybin — full drug profile →
- Integration sessions
Conditions studied
- Psychological Stress — all drugs for Psychological Stress →
- Depression — all drugs for Depression →
- Anxiety — all drugs for Anxiety →
Sponsor
Rachel Yehuda
Who can join
18 and older, any sex, with Psychological Stress or Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an open-label psilocybin-assisted therapy study that will examine the safety and tolerability of psilocybin-assisted therapy in the offspring of genocide survivors with mood and anxiety disorders. The study will also investigate the efficacy of psilocybin-assisted therapy in reducing symptoms such as depression, anxiety and stress, as well as changes to the psychological effects of parental exposure to genocide, and changes to psychological resilience.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06899165
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Psilocybin
Trials testing the same drug.
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- NCT07499583 — Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, PHASE2 · not yet recruiting
- NCT07226232 — Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · not yet recruiting
- NCT07336238 — Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or · Phase 2 · recruiting
- NCT07506395 — Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder · Phase 1 · not yet recruiting
Other recruiting trials for Psychological Stress
Currently open trials in the same condition.
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- NCT06899308 — Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees · recruiting
- NCT06788106 — Effect of Aerobic Exercise With Synchronous Music on Functions Among Medical Students · NA · recruiting
- NCT06795061 — Fitness Buddy Program to Boost Physical Activity in University Students · NA · active not recruiting
- NCT06878885 — Trauma and Cardiometabolic Health in an American Indian Community · NA · recruiting
Other Rachel Yehuda trials
Trials by the same sponsor.
- NCT07102576 — MDMA-Assisted Therapy for Mental Healthcare Providers · Phase 1 · recruiting
- NCT04924166 — PTSD Prevention Using Oral Hydrocortisone · Phase 2 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06899165 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rachel Yehuda
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06899165.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing