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NCT06892665
The Effect of HPI to Reduce Intraoperative Hypotension in Caesarean Sections
NA trial testing Hypotension prediction index in Pregnancy Related in 100 participants. Currently enrolling.
31 October 2025
Quick facts
| Lead sponsor | National University of Malaysia |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 1 January 2025 |
| Primary completion | 31 October 2025 |
| Estimated completion | 31 January 2026 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- Hypotension prediction index
- Non invasive Blood Pressure Monitoring
Conditions studied
- Pregnancy Related — all drugs for Pregnancy Related →
- Hypotension — all drugs for Hypotension →
- Maternal-Fetal Relations — all drugs for Maternal-Fetal Relations →
- Cesarean Section Complications — all drugs for Cesarean Section Complications →
Sponsor
National University of Malaysia
Who can join
Adults 18 to 40, female only, with Pregnancy Related or Hypotension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
During caesarean section, blood pressure variations especially a reduction in blood pressure (or hypotension) can bring harmful effects to mother and baby. This usually occurs after spinal anaesthesia is administered. Usually, the anaesthetist will treat hypotension as it occurs. However, a new medical device is now available to predict hypotension. It is called the Hypotension Prediction Index (HPI). This device allows the prediction of hypotension; hence, treatment can be given before it occurs. It has been widely utilised in major surgeries like abdominal tumour surgery and cardiac surgery worldwide and has shown a substantial reduction in hypotension. This study aims to determine whether the duration and severity of hypotension can be reduced when HPI is used in lower segment caesarean sections. The secondary objective of the study is to determine if the complication rate can be reduced in both mother and baby.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06892665
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06892665 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National University of Malaysia
- Last refreshed: 23 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06892665.
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