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NCT06891248
The Utility of Osteopathic Manipulative Medicine in Weaning Patients from the Ventilator Pilot Trial
NA trial testing Osteopathic Manipulative Treatment in Respiratory Failure in 20 participants. Not yet recruiting.
8 June 2025
Quick facts
| Lead sponsor | Oklahoma State University Center for Health Sciences |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 17 March 2025 |
| Primary completion | 8 June 2025 |
| Estimated completion | 8 June 2025 |
Drugs / interventions tested
- Osteopathic Manipulative Treatment
Conditions studied
- Respiratory Failure — all drugs for Respiratory Failure →
- Osteopathy in Diseases Classified Elsewhere — all drugs for Osteopathy in Diseases Classified Elsewhere →
Sponsor
Oklahoma State University Center for Health Sciences
Who can join
Adults 18 to 85, any sex, with Respiratory Failure or Osteopathy in Diseases Classified Elsewhere. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objectives of this research are to determine the treatment effect size of OMM to wean patients off of the ventilator, determine the number of patients needed for a larger study (power), determine the willingness of patients/POAs to be recruited, identify the correct dosing of OMM and whether there are concerns for the safety of treatment, and determine whether the hypothesis is feasible for a larger study. The primary outcome measure is the duration of time until a subject is weaned off of mechanical ventilation using Osteopathic Manipulative Medicine (OMM). The secondary outcome measures (see the next section for further explanation) are to determine if OMM affects changes in morbidity and mortality, such as VBG/ABG, NIF, RSBI, P 0.1, FiO2, PEEP, mental status, hemodynamic stability (blood pressure), spontaneous TV, reintubation after extubation, and death.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06891248
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Osteopathic Manipulative Treatment
Trials testing the same drug.
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- NCT06570395 — Osteopathic Manipulative Treatment in the Third Trimester of Pregnancy · terminated
- NCT06471426 — The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction · NA · recruiting
Other recruiting trials for Respiratory Failure
Currently open trials in the same condition.
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- NCT07359261 — Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients · Phase 2 · recruiting
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- NCT07114289 — Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients · NA · recruiting
- NCT06591533 — The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubation Proces · NA · recruiting
Other Oklahoma State University Center for Health Sciences trials
Trials by the same sponsor.
- NCT05891587 — Semaglutide Therapy for Alcohol Reduction - Tulsa · Phase 2 · completed
- NCT05773833 — Indigenous Supported Agriculture "Go Healthy" · NA · completed
- NCT04990492 — Interactive Voice Based Administration of the GAD 7 · NA · unknown
- NCT04964726 — Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity · NA · completed
- NCT04609267 — Interactive Voice-Based Administration of the PHQ-9 · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06891248 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oklahoma State University Center for Health Sciences
- Last refreshed: 24 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06891248.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing