NCT06886438 is a NA clinical trial of RVS in Necrotic Pulp, sponsored by Saglik Bilimleri Universitesi.

Who is sponsoring NCT06886438?

NCT06886438 is sponsored by Saglik Bilimleri Universitesi.

What drugs are being tested in NCT06886438?

Interventions in NCT06886438: RVS, L-PRF, i-PRF.

What condition does NCT06886438 study?

NCT06886438 studies Necrotic Pulp, Regenerative Endodontic Procedures, Mature Teeth, Apical Periodontitis, PRF, Discoloration of Teeth.

Is NCT06886438 still recruiting?

NCT06886438 is currently completed. Last updated 20 March 2025.

Last reviewed 2025-03-20 · How we verify

NCT06886438

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial

Completed NA Last updated 20 March 2025

What this trial tests

NA trial testing RVS in Necrotic Pulp in 48 participants. Completed in 24 January 2025.

Timeline

3 February 2024

Primary endpoint
10 March 2024

24 January 2025

Quick facts

Lead sponsor	Saglik Bilimleri Universitesi
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	48
Start date	3 February 2024
Primary completion	10 March 2024
Estimated completion	24 January 2025
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

RVS
L-PRF
i-PRF

Conditions studied

Necrotic Pulp — all drugs for Necrotic Pulp →
Regenerative Endodontic Procedures — all drugs for Regenerative Endodontic Procedures →
Mature Teeth — all drugs for Mature Teeth →
Apical Periodontitis — all drugs for Apical Periodontitis →

Sponsor

Saglik Bilimleri Universitesi — full company profile →

Who can join

Adults 14 to 65, any sex, with Necrotic Pulp or Regenerative Endodontic Procedures. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study investigates a biological approach that allows infected and necrotic teeth to heal themselves instead of being treated with traditional root canal therapy. Traditional root canal treatment involves cleaning the infected tissue inside the tooth and sealing it with a filling material, whereas regenerative endodontic treatment is a novel approach that enables the tooth to repair itself. This treatment method involves inducing bleeding in the root area or applying special blood derivatives (PRF types) to accumulate healing-supporting cells and growth factors. The aim of the study is to compare the effects of different biological treatment methods on the healing process, postoperative pain, and tooth discoloration. The results may help develop more effective and aesthetically successful treatment options in the future.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Necrotic Pulp

Currently open trials in the same condition.

NCT07310212 — Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques · NA · recruiting

Other Saglik Bilimleri Universitesi trials

Trials by the same sponsor.

NCT07499986 — Respiratory Muscle Training in Patients Undergoing Lung Cancer Surgery · NA · not yet recruiting
NCT07516340 — Gamification-Based Peer Education in Nursing Students: Effects on Sexual Health Literacy and Attitudes · NA · not yet recruiting
NCT07520435 — Short-Term Mindfulness Intervention for Anxiety and Maternal Attachment in NICU Mothers · NA · not yet recruiting
NCT07528001 — Hypno-Breastfeeding Education and Postpartum Outcomes · NA · not yet recruiting
NCT07344649 — Turkish Validation of the Nijmegen Questionnaire in COPD · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06886438 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi
Last refreshed: 20 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06886438.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing