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NCT06886243
Menstrual Cycle Effects on Postoperative Sensitivity and Rebound Pain in Composite Restorations
NA trial testing Direct Posterior Composite Restoration in Postoperative Sensitivity in 35 participants. Completed in 30 June 2023.
20 February 2023
Quick facts
| Lead sponsor | Firat University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 35 |
| Start date | 1 August 2022 |
| Primary completion | 20 February 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Direct Posterior Composite Restoration
Conditions studied
- Postoperative Sensitivity — all drugs for Postoperative Sensitivity →
- Rebound Pain — all drugs for Rebound Pain →
- Menstrual Cycle — all drugs for Menstrual Cycle →
- Composite Restorations — all drugs for Composite Restorations →
Sponsor
Firat University
Who can join
Adults 18 to 45, female only, with Postoperative Sensitivity or Rebound Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate how different phases of the menstrual cycle affect pain after dental treatments. Specifically, it investigates two types of pain: Postoperative sensitivity (pain felt after the filling procedure), and Rebound pain (pain that begins after the numbness from anesthesia wears off). The study was conducted with 35 women who received two dental fillings at different times in their cycle: once during the menstrual phase and once during the ovulatory phase. A local anesthetic (inferior alveolar nerve block) was used before treatment, and pain was measured using a 0-10 visual scale at several time points after the procedure. The goal of the study is to understand whether hormonal changes during the menstrual cycle can affect pain levels after dental work. This information could help dentists improve pain management strategies for women and personalize treatment timing.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06886243
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06886243 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Firat University
- Last refreshed: 25 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06886243.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing