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NCT06885983
Healing After Augmentation of Alveolar Ridge Using Collagen Membrane
NA trial testing implant placement in Bone Healing in 90 participants. Enrolling by invitation.
1 November 2027
Quick facts
| Lead sponsor | University of Belgrade |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 7 March 2025 |
| Primary completion | 1 November 2027 |
| Estimated completion | 1 November 2029 |
| Sites | 1 location across Serbia |
Drugs / interventions tested
- implant placement
- Guided bone regeneration
Conditions studied
- Bone Healing — all drugs for Bone Healing →
- Augmentation — all drugs for Augmentation →
- Augmentation, Alveolar Ridge — all drugs for Augmentation, Alveolar Ridge →
Sponsor
University of Belgrade
Who can join
Adults 18 to 65, any sex, with Bone Healing or Augmentation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
One of the prerequisites for successful prosthetic implant therapy of patients is achieving the initial stability of the embedded implant, which largely depends on the width alveolar ridge, at the place of its installation. Regenerative therapy of the horizontal dimension of the alveolar ridge simultaneously with the installation of implants is carried out using biocompatible materials; a basket of thin ones substitutes and collagen membranes. Clinical application of the collagen matrix to date has shown successful regeneration soft tissue in corrective surgery of the oral mucosa, by increasing the volume of the gingiva, approximately as effective as the application of a connective tissue graft from the palate. In the current literature, there is no data on the cellular effects of the regeneration of soft, a especially bone tissue, after the application of a membrane with cross-linked collagen type I, u regenerative therapy of fenestrations, dehiscence and buccal contour augmentations bone lamellae, simultaneously with implant placement. Also, tissue monitoring mechanisms of regeneration of soft and bone tissue, has not been shown in the literature so far controlled and systematized results using the Primescan digital program scans and software analysis of soft tissue regeneration parameters, as well as their own correlations with CBCT and clinical analysis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06885983
- Europe PMC full search
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Related trials
Other trials of implant placement
Trials testing the same drug.
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- NCT06176014 — Effect of Using (PEKK) Framework Versus (Co- Cr) Framework on The Bone of Mandibular Implant Supported Hybrid Prostheses · NA · completed
Other recruiting trials for Bone Healing
Currently open trials in the same condition.
- NCT06624982 — Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation · recruiting
- NCT06711744 — ISQ Differences Between Different Implants in Post-extraction Sockets · NA · recruiting
- NCT07190950 — Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction · NA · recruiting
Other University of Belgrade trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06885983 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Belgrade
- Last refreshed: 25 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06885983.
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