NCT06884332 (SPINAL) is a NA clinical trial of Sparing irradiation in Bone Metastasis, sponsored by Institut de Cancérologie de Lorraine.

Who is sponsoring NCT06884332?

NCT06884332 is sponsored by Institut de Cancérologie de Lorraine.

What drugs are being tested in NCT06884332?

Interventions in NCT06884332: Sparing irradiation, Conventional spinal irradiation.

What condition does NCT06884332 study?

NCT06884332 studies Bone Metastasis, Oncology Pain.

Is NCT06884332 still recruiting?

NCT06884332 is currently recruiting now. Last updated 23 September 2025.

Last reviewed 2025-09-23 · How we verify

NCT06884332: SPINAL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Spinal Palliation in Irradiation for Neoplastic Analgesia and Life Quality

Recruiting now NA Last updated 23 September 2025

What this trial tests

NA trial testing Sparing irradiation in Bone Metastasis in 598 participants. Currently enrolling.

Timeline

2 July 2025

Primary endpoint
2 July 2027

2 January 2029

Quick facts

Lead sponsor	Institut de Cancérologie de Lorraine
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	598
Start date	2 July 2025
Primary completion	2 July 2027
Estimated completion	2 January 2029
Sites	4 locations across France

Drugs / interventions tested

Sparing irradiation
Conventional spinal irradiation

Conditions studied

Bone Metastasis — all drugs for Bone Metastasis →
Oncology Pain — all drugs for Oncology Pain →

Sponsor

Institut de Cancérologie de Lorraine — full company profile →

Who can join

18 and older, any sex, with Bone Metastasis or Oncology Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to assess the impact of reducing the volume of palliative metastatic bone irradiation on analgesic effectiveness at day 30 and to evaluate the efficiency of telemonitoring in identifying patients who could benefit from Patient-Reported Outcomes (PROs) and require care. These objectives will be addressed in a multicenter, randomized, prospective study with two arms: A standard arm with spinal irradiation without sparing the adjacent vertebrae. An experimental arm with spinal irradiation sparing the adjacent vertebrae. The results will determine whether reducing the irradiated volume can maintain effective pain relief while minimizing side effects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

SPINAL: study protocol for a multicenter non-inferiority trial evaluating reduce vertebral irradiation volumes in palliative radiotherapy for spinal bone metastases on analgesic efficacy.
Faivre JC, Lambert A, Bruand M, Francais A, et al · · 2026 · PMID 42032485 · DOI 10.1186/s12885-026-16053-8

Verify or expand the search:

Other recruiting trials for Bone Metastasis

Currently open trials in the same condition.

NCT06806462 — Biomolecular Markers of Bone Metastasis · NA · recruiting

Other Institut de Cancérologie de Lorraine trials

Trials by the same sponsor.

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NCT07165756 — "Mon Parcours de Vie" Localized Breast Cancer: Announcement, Support, Information on the Disease and Treatments. Pilot S · recruiting
NCT06903104 — Acceptability and Feasibility of a Stress Prevention Program Based on Meditation and Acceptance and Commitment Therapy f · NA · completed
NCT06552091 — Guided Digital Self-Hypnosis Solution for Managing Hot Flashes in Patients Undergoing Adjuvant Hormone Therapy · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06884332 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Institut de Cancérologie de Lorraine
Last refreshed: 23 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06884332.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing