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NCT06878443: PROBPROM-Pilot
Vaginal Probiotics During Pregnancy After Premature Rupture of Membranes
NA trial testing Vaginal probiotics in Pregnancy. Withdrawn.
17 June 2025
Quick facts
| Lead sponsor | Centre hospitalier de l'Université de Montréal (CHUM) |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Start date | 17 June 2025 |
| Primary completion | 17 June 2025 |
| Estimated completion | 17 June 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Vaginal probiotics
Conditions studied
- Pregnancy — all drugs for Pregnancy →
- Prematurity — all drugs for Prematurity →
- PPROM — all drugs for PPROM →
Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Who can join
18 and older, female only, with Pregnancy or Prematurity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare the microbiota of preterm babies born after premature breaking water with full-term babies microbiota. The main questions it aims to answer are: * Is babies' microbiota differs with premature water breaking than full-term babies microbiota? * Is vaginal probiotics given to the mother influence the baby microbiota? Researchers will compare vaginal probiotics use to no treatment to see if the babies microbiota and mother microbiota is influenced. Participants will * Take vaginal probiotics between premature breaking water until delivery (group A) * Keep a diary of their symptoms and compliance to treatment (group A) * Take samples of vaginal secretions and of baby's stool (all groups)
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06878443
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Centre hospitalier de l'Université de Montréal (CHUM) trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06878443 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre hospitalier de l'Université de Montréal (CHUM)
- Last refreshed: 4 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06878443.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing