NCT06877780 is a NA clinical trial of RMR with SME in Class III Malocclusion, sponsored by Damascus University.

Who is sponsoring NCT06877780?

NCT06877780 is sponsored by Damascus University.

What drugs are being tested in NCT06877780?

Interventions in NCT06877780: RMR with SME, BAIMT with RME.

What condition does NCT06877780 study?

NCT06877780 studies Class III Malocclusion, Maxillary Deficiency.

Is NCT06877780 still recruiting?

NCT06877780 is currently completed. Last updated 17 March 2025.

Last reviewed 2025-03-17 · How we verify

NCT06877780

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures

Completed NA Last updated 17 March 2025

What this trial tests

NA trial testing RMR with SME in Class III Malocclusion in 24 participants. Completed in 1 September 2023.

Timeline

1 September 2021

Primary endpoint
15 July 2022

1 September 2023

Quick facts

Lead sponsor	Damascus University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	24
Start date	1 September 2021
Primary completion	15 July 2022
Estimated completion	1 September 2023
Sites	1 location across Syria

Drugs / interventions tested

RMR with SME
BAIMT with RME

Conditions studied

Class III Malocclusion — all drugs for Class III Malocclusion →
Maxillary Deficiency — all drugs for Maxillary Deficiency →

Sponsor

Damascus University

Who can join

Adults 12 to 15, any sex, with Class III Malocclusion or Maxillary Deficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A clinical examination of each recalled candidate patient will be carried out at Adib Al Lahham Centre at the Ministry of Health Damascus to ensure that he/she meets the inclusion criteria. Following obtaining the full records, including a lateral cephalometric radiograph, additional checking will be made to classify the skeletal relationship (class III relationship) of each possible candidate for this work. This trial compares two groups of patients who suffered from Class III malocclusion associated with maxillary constriction. Experimental Group: Patients in this group will undergo treatment using bone-anchored intermaxillary traction (BAIMT) associated with rapid maxillary expansion (RME). Control Group: Patients in this group will undergo treatment using a removable mandibular retractor (RMR) associated with slow maxillary expansion (SME).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of Patient-reported Outcome Measures during the Correction of Skeletal Class III Malocclusion with Maxillary Constriction in Early Adolescence.
Zakaria AS, Hassan R, Baharin F, Alfailany DT, et al · · 2025 · PMID 41040030 · DOI 10.5005/jp-journals-10024-3901

Verify or expand the search:

Other recruiting trials for Class III Malocclusion

Currently open trials in the same condition.

NCT07162753 — Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System · recruiting

Other Damascus University trials

Trials by the same sponsor.

NCT07532161 — Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery · NA · not yet recruiting
NCT07515612 — The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic. · NA · recruiting
NCT07272798 — Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension · recruiting
NCT07426523 — Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. · NA · completed
NCT07366788 — Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06877780 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Damascus University
Last refreshed: 17 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06877780.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing