Rapid Evacuation and Access of Cerebral Hemorrhage Trial (REACH)

NCT06870812 NA RECRUITING

The main purpose of this study is to compare patients with a deep bleed in the brain undergoing surgery to patients receiving routine medical care. The standard treatment involves admission to the Intensive Care Unit (ICU) with close monitoring and blood pressure control. It also includes other medical (non-surgical) treatments to prevent more bleeding or another stroke. Sometimes, doctors will recommend surgery to remove the blood if medical treatment alone is not successful. There is evidence that doing minimally invasive surgery early-using a small opening in the skull to remove blood-may help some patients. Researchers aim to understand whether this surgery is better than current medical treatment, which may include surgeries to relieve pressure on the brain in some cases. This study, called REACH, is comparing usual medical care to early minimally invasive surgery so doctors can know which is better for patients.

Details

Lead sponsor	Emory University
Phase	NA
Status	RECRUITING
Enrolment	600
Start date	2025-05-27
Completion	2030-03

Conditions

• Stroke Hemorrhagic

Interventions

• Surgical management
• Medical Management

Primary outcomes

• Score on the modified Rankin Scale (mRS) at — 180 days after randomization
  The mRS is a seven-level ordinal scale that ranges from 0 (no symptoms) to 6 (death).

Countries

United States