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Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section (bupivacaine)
Our hypothesis is that the bupivacaine dose determined according to the thoracolumbar vertebral body length (VBL) is more effective in achieving a lower hypotension rate during spinal anesthesia for cesarean delivery than the dose usually adjusted based on height and weight. The VBL measurements were determined from the midpoint of C7 to the tuffier line L4 spinous process. Method: Patients ranging in height from 150 to 170 were randomly assigned to either Group 1 (0.2 mg of 0.5% hyperbaric bupivacaine per cm VBL or Group 2 (height-adjusted dose of 0.5% hyperbaric bupivacaine based on a minimum dose of 0.065 mg/cm according to height) or Group 3 (height-adjusted dose of 0.5% hyperbaric bupivacaine based on a minimum height-adjusted dose of 0.065 mg/cm).
Details
| Lead sponsor | TC Erciyes University |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 285 |
| Start date | Tue May 20 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Dec 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Obstetric Anesthesia Problems
- Bupivacaine Adverse Reaction
Interventions
- Group VBL (Thoracolumbal vertebral body length) received 0.2 mg x VBL cm of %0.5 hyperbaric bupivacaine
- Group FD (fixed dose) received a volume of 0.5% hyperbaric bupivacaine based on a dose calculated according to the patient's height 0.065 mg/cm
- Group AD (adjusted dosage) got intrathecal heavy bupivacaine (0.5%) tailored to the patient's height and weight.
Countries
Turkey (Türkiye)