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NCT06869304
The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases
trial testing Montreal Cognitive Assessment in Neurocognitive Disorder in 56 participants. Not yet recruiting.
15 April 2025
Quick facts
| Lead sponsor | Ankara City Hospital Bilkent |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 56 |
| Start date | 15 March 2025 |
| Primary completion | 15 April 2025 |
| Estimated completion | 30 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Montreal Cognitive Assessment
Conditions studied
- Neurocognitive Disorder — all drugs for Neurocognitive Disorder →
- Robotic Assisted Laparoscopic Radical Prostatectomy — all drugs for Robotic Assisted Laparoscopic Radical Prostatectomy →
- Near Infrared Spectroscopy — all drugs for Near Infrared Spectroscopy →
Sponsor
Ankara City Hospital Bilkent
Who can join
Adults 65 to 100, male only, with Neurocognitive Disorder or Robotic Assisted Laparoscopic Radical Prostatectomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period. Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06869304
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Other recruiting trials for Neurocognitive Disorder
Currently open trials in the same condition.
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Other Ankara City Hospital Bilkent trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06869304 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ankara City Hospital Bilkent
- Last refreshed: 11 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06869304.
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