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NCT06866392: CC-AZ
Study on Novel Strategies for Cervical Cancer Screening Using Photoelectric Detection and Epigenetic Procotol
trial testing photoelectric detection in Cervical Cancer in 4,200 participants. Not yet recruiting.
15 March 2027
Quick facts
| Lead sponsor | Peking Union Medical College Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 4,200 |
| Start date | 15 March 2025 |
| Primary completion | 15 March 2027 |
| Estimated completion | 15 March 2028 |
Drugs / interventions tested
- photoelectric detection
Conditions studied
- Cervical Cancer — all drugs for Cervical Cancer →
- Cervical Intraepithelial Neoplasia — all drugs for Cervical Intraepithelial Neoplasia →
Sponsor
Peking Union Medical College Hospital
Who can join
Adults 18 to 65, female only, with Cervical Cancer or Cervical Intraepithelial Neoplasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A national multicenter, open randomized controlled study was conducted. It is planned to invite 30 multi-center units across the country to compete for enrollment, and each multi-center will enroll 140 patients meeting colposcopic indications (70 in the conventional group and 70 in the experimental group), totaling 4200 patients. Enrolled subjects were randomly divided into two groups. Methylation test + colposcopic biopsy was performed in the conventional group, and clinical follow-up was performed according to the methylation results; in the experimental group, methylation test + colposcopic biopsy +OITS was performed, and clinical follow-up was performed according to the methylation results and OITS results. To verify the effectiveness of methylation tests and OITS in screening for CIN2+, whether they can reduce missed diagnosis of CIN2+, whether they can flag excessive colposcopic procedures, and the value of clinical follow-up for cervical lesions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Human papillomavirus-mediated cervical cancer: epigenetic interplay and clinical implications.
Sisodiya S, Singh P, Joshi T, Aftab M, et al · · 2025 · cited 4× · PMID 41113635 · DOI 10.3389/fmicb.2025.1633283
Verify or expand the search:
- PubMed search for NCT06866392
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Peking Union Medical College Hospital trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06866392 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking Union Medical College Hospital
- Last refreshed: 10 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06866392.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing