Last reviewed · How we verify
NCT06857162
Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning
NA trial testing Positioninng during Cs in This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes in 216 participants. Not yet recruiting.
1 August 2025
Quick facts
| Lead sponsor | Aswan University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 216 |
| Start date | 25 April 2025 |
| Primary completion | 1 August 2025 |
| Estimated completion | 1 September 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Positioninng during Cs
Conditions studied
- This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes — all drugs for This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes →
- Maternal Hemodynamic — all drugs for Maternal Hemodynamic →
- Maternal Positioning During CS — all drugs for Maternal Positioning During CS →
Sponsor
Aswan University
Who can join
Adults 20 to 40, female only, with This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes or Maternal Hemodynamic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes . Hemodynamic instability, such as hypotension following spinal anesthesia, is a frequent complication and can lead to adverse maternal and neonatal outcomes. Traditionally, after spinal anesthesia, women are positioned supine, sometimes with a slight left lateral tilt to mitigate the risk of aortocaval compression . However, recent studies and clinical observations suggest that delayed supine positioning-keeping the patient in a sitting or semi-sitting position for a period following spinal anesthesiamay improve hemodynamic stability. These alternative positions may help to mitigate the abrupt drop in blood pressure commonly seen after spinal anesthesia by allowing for a more gradual redistribution of blood volume . Understanding the optimal positioning strategy could lead to improved clinical protocols that enhance maternal and fetal safety. By comparing immediate supine positioning with delayed supine positioning (in sitting and semi-sitting positions), this study aims to provide evidence on which positioning strategy offers the best hemodynamic outcomes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Post-spinal position and its impact on hemodynamic, block height, and comfort in caesarean delivery: A randomized assessor-blinded trial.
Mohamady Eldemrdash A, Elabd Hassan I, Youssef Mohamed A, Ahmed Raslan HM. · · 2026 · PMID 41871806 · DOI 10.1016/j.redare.2026.502089
Verify or expand the search:
- PubMed search for NCT06857162
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Aswan University trials
Trials by the same sponsor.
- NCT07232238 — TRPM2 Gene Polymorphism, NLRP3 Inflammasome Expression in Vitiligo Patients · active not recruiting
- NCT07140640 — Effect of a 20% Reduction in Hyperbaric Bupivacaine Dose on High Spinal Block Incidence in Cesarean Delivery: A Risk-Str · Phase 4 · not yet recruiting
- NCT07466719 — Comparison of Efficacy and Safety of Manual Syringing Versus Pneumatic Pressure Bag for Blood Transfusion in Patients Un · NA · recruiting
- NCT07320872 — Correlation Between Vaspin Gene Polymorphism and Serum Vaspin Levels in Psoriasis Vulgaris · recruiting
- NCT07109947 — Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of Miscarriage · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06857162 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aswan University
- Last refreshed: 19 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06857162.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing