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NCT06839963: K-LUS
Kinshasa Lung Ultrasound Approach Validation
trial in Respiratory Disease in 178 participants. Completed in 16 May 2025.
16 May 2025
Quick facts
| Lead sponsor | University of Oxford |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 178 |
| Start date | 1 January 2025 |
| Primary completion | 16 May 2025 |
| Estimated completion | 16 May 2025 |
| Sites | 3 locations across Bangladesh, Democratic Republic of the Congo, Sierra Leone |
Conditions studied
- Respiratory Disease — all drugs for Respiratory Disease →
- Children, Only — all drugs for Children, Only →
Sponsor
University of Oxford
Who can join
Adults 3 Months to 14, any sex, with Respiratory Disease or Children, Only. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study team will perform a prospective, observational study in two sites in the Democratic Republic of Congo (DRC) and Bangladesh in children aged 3 months to 14 years, admitted to hospital with acute respiratory symptoms. The Kinshasa lung ultrasound (K-LUS) approach integrates existing WHO clinical guidelines, lung ultrasound diagnostic accuracy evidence and paediatric ultrasound guidelines. The approach was built using a modified Delphi technique and integrates six LUS profiles, two clinical history features (timing of onset, trauma) and one clinical examination feature (fever) to suggest one among 10 clinical diagnosis. After the initial diagnosis is established by the treating physician, a research assistant will perform a LUS examination and apply the K-LUS approach. Comparison between the K-LUS derived diagnosis and the clinical diagnosis will be performed. After patient discharge a panel will also establish the most likely diagnosis according to all information available during patient stay. This study is funded by the Wellcome Trust (ITPA grant) ref: WT-ITPA 2021/001
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Abstracts of the ICARE 2025 79th SIAARTI National Congress.
· 2025 · PMID 41111139 · DOI 10.1186/s44158-025-00273-8
Verify or expand the search:
- PubMed search for NCT06839963
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06839963 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oxford
- Last refreshed: 24 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06839963.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing