Last reviewed · How we verify
NCT06835894
Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation
trial in Video-Assisted Thoracoscopic Surgery in 115 participants. Not yet recruiting.
1 July 2025
Quick facts
| Lead sponsor | Koç University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 115 |
| Start date | 1 April 2025 |
| Primary completion | 1 July 2025 |
| Estimated completion | 10 July 2025 |
Conditions studied
- Video-Assisted Thoracoscopic Surgery — all drugs for Video-Assisted Thoracoscopic Surgery →
- One-Lung Ventilation — all drugs for One-Lung Ventilation →
- Capnography — all drugs for Capnography →
- Blood Gas Analysis — all drugs for Blood Gas Analysis →
Sponsor
Koç University
Who can join
18 and older, any sex, with Video-Assisted Thoracoscopic Surgery or One-Lung Ventilation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, we want to find out if measuring carbon dioxide from a patient's breath (end-tidal CO₂ or ETCO₂) can reliably reflect changes in blood carbon dioxide levels (arterial CO₂ or PaCO₂) during lung surgery. Instead of just looking at individual values, we are specifically investigating whether ETCO₂ and PaCO₂ rise and fall in the same direction over time. During lung surgery, patients often need "one-lung ventilation," where only one lung is used for breathing while the other is deflated to help the surgeon. This can cause carbon dioxide levels in the blood to change, which are typically monitored by taking blood samples. If ETCO₂ trends closely follow PaCO₂ trends, doctors may not need to take as many blood samples. Patients in this study will already have a small tube in an artery for monitoring blood pressure. Whenever a blood test is taken, we will compare the blood CO₂ level with the ETCO₂ reading at that moment. We will also track heart rate, blood pressure, and body temperature. By comparing these measurements, we hope to learn whether ETCO₂ reliably follows the same trends as PaCO₂, making it a useful tool for monitoring carbon dioxide levels in lung surgery with fewer blood tests.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06835894
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Video-Assisted Thoracoscopic Surgery
Currently open trials in the same condition.
- NCT07201285 — Edge of Laminar Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surg · NA · recruiting
- NCT06837519 — Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted · NA · recruiting
- NCT05145153 — Incidence of Chronic Pain After Thoracic Surgery · recruiting
Other Koç University trials
Trials by the same sponsor.
- NCT07528976 — Effect of Peer Education on Climate Change Awareness and Anxiety in Nursing Students · NA · recruiting
- NCT07445711 — Effect of Guided Imagery and AI-Assisted Video on Pain During Uterine Involution Assessment in Postpartum Women: A Rando · NA · not yet recruiting
- NCT07341113 — Positional Effects on Lung Ventilation and Perfusion in Obesity · completed
- NCT07171944 — Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in In · NA · not yet recruiting
- NCT07409818 — A Novel Classification in Calcific Tendinitis of the Shoulder: Evaluating MRI Localization and Related Treatment Strateg · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06835894 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Koç University
- Last refreshed: 19 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06835894.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing