Last reviewed · How we verify
NCT06834594: BOOST
Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome
Phase 4 trial testing Micronized progesterone 200 MG in Turner Syndrome in 40 participants. Currently enrolling.
30 July 2026
Quick facts
| Lead sponsor | Children's Mercy Hospital Kansas City |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 31 July 2025 |
| Primary completion | 30 July 2026 |
| Estimated completion | 31 July 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Micronized progesterone 200 MG — full drug profile →
- Micronized Progesterone 100 MG — full drug profile →
Conditions studied
- Turner Syndrome — all drugs for Turner Syndrome →
- Primary Ovarian Insufficiency (Poi) — all drugs for Primary Ovarian Insufficiency (Poi) →
Sponsor
Children's Mercy Hospital Kansas City
Who can join
Adults 12 to 20, female only, with Turner Syndrome or Primary Ovarian Insufficiency (Poi). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06834594
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Turner Syndrome
Currently open trials in the same condition.
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- NCT06794190 — Characterization of Hepatopathy in Turner Syndrome: Analysis of Determinants · recruiting
- NCT06780514 — Cardiopulmonary Exercise Testing in Girls (8-18y) with Turner Sydrome. · NA · recruiting
- NCT05723835 — A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9 · Phase 3 · active not recruiting
- NCT05740579 — The Danish TURNER Cryopreservation Study · NA · recruiting
Other Children's Mercy Hospital Kansas City trials
Trials by the same sponsor.
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- NCT06738121 — Cosmetic Outcomes of Umbilical Hernia Incisions · NA · completed
- NCT06520657 — Addressing Social Determinants of Health in Child Obesity Treatment Using Community Health Workers · NA · active not recruiting
- NCT06554288 — Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06834594 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Children's Mercy Hospital Kansas City
- Last refreshed: 4 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06834594.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing