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NCT06834464
Effect of Nanohydroxyapatite Paste After Different Pretreatment Techniques on White Spot White Spot Lesions
NA trial testing Nanohydroxyapatite paste in White Spot Lesions in 40 participants. Completed in 30 January 2025.
20 January 2025
Quick facts
| Lead sponsor | National Research Centre, Egypt |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 5 December 2024 |
| Primary completion | 20 January 2025 |
| Estimated completion | 30 January 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Nanohydroxyapatite paste — full drug profile →
- HCl liquid
- microabrasion — full drug profile →
Conditions studied
- White Spot Lesions — all drugs for White Spot Lesions →
Sponsor
National Research Centre, Egypt — full company profile →
Who can join
Adults 10 to 14, any sex, with White Spot Lesions. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
forty teeth diagnosed with white spot lesions in children aged between 10-14 years old were selected to compare between the effect of using nanohydroxyapatite paste applicatio either alone or preceded by the application of HCl (hydrochloric acid) or microabrasion
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of nanohydroxyapatite paste after different pretreatment techniques on remineralization and color change of white spot lesions in children: a randomized control study.
El Mansy MM, Saleh RS, Rashed MF, El-Motayam AK. · · 2026 · PMID 41530802 · DOI 10.1186/s12903-025-07365-5
Verify or expand the search:
- PubMed search for NCT06834464
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for White Spot Lesions
Currently open trials in the same condition.
- NCT07426432 — Evaluate the Effect of Fluoride-Releasing Composite Resin on Prevention of White Spot Lesions During Clear Aligner Thera · NA · active not recruiting
- NCT06616207 — Topical 10% Povidone-Iodine in Preventing White Spots · Phase 2 · recruiting
- NCT06696105 — Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions · Phase 4 · active not recruiting
- NCT05733676 — Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment · NA · recruiting
Other National Research Centre, Egypt trials
Trials by the same sponsor.
- NCT07138586 — Evaluation of Low Level Laser Therapy and Lidocaine Versus Chlorhexidine for the Management of Traumatic Oral Ulcers in · NA · completed
- NCT06872827 — Effect of Herbal Toothpaste Versus Conventional One on Black Stains · NA · completed
- NCT06821724 — Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children · NA · completed
- NCT06131879 — Laser Versus Physiotherapy in Management of Bruxism in Children: RCS · NA · completed
- NCT06561724 — Diet Supplementation With Prebiotics to Improve Gut Health in Egyptian Children · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06834464 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Research Centre, Egypt
- Last refreshed: 24 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06834464.
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