Last reviewed · How we verify
NCT06834334: TightT1
Clinical Effectiveness of Advanced Hybrid Closed-loop Systems for Achieving Time in Tight Range Among T1D Patients
trial testing MM780G in Type 1 Diabetes (T1D) in 189 participants. Completed in 1 October 2025.
1 October 2025
Quick facts
| Lead sponsor | Castilla-La Mancha Health Service |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 189 |
| Start date | 27 February 2025 |
| Primary completion | 1 October 2025 |
| Estimated completion | 1 October 2025 |
| Sites | 3 locations across Spain |
Drugs / interventions tested
- MM780G
- TTSX2
- CamAPS
Conditions studied
- Type 1 Diabetes (T1D) — all drugs for Type 1 Diabetes (T1D) →
Sponsor
Castilla-La Mancha Health Service — full company profile →
Who can join
Adults 18 to 99, any sex, with Type 1 Diabetes (T1D). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Diabetes is a chronic disease with a relevant public health burden. Maintaining blood glucose levels as close to normal as possible is essential to avoid the associated microvascular and macrovascular complications. Therefore, the key to prevent and/or reduce the development of these chronic complications lies in an adequate and strict glycemic control. This study consist of a cross-sectional observational study among adult patients with type 1 diabetes (T1D). The main objective is to analyze the effect on time in tight range (TiTR, 70-140 mg/dL) of interstitial glucose between three different advanced hybrid closed-loop (AHCL) systems.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06834334
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Type 1 Diabetes (T1D)
Currently open trials in the same condition.
- NCT07011147 — Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery · NA · recruiting
- NCT06782568 — Avoidance of Insulin-induced Lipohypertophy in People With Diabetes Using Ultrasound Scanning Within Diabetes Clinics · NA · recruiting
- NCT07470593 — Study of Glucose Tolerance Abnormalities Using Continuous Glucose Monitoring for the Identification of Early Loss of Pan · recruiting
- NCT07356089 — Twiist Postmarket Surveillance Study for Type 1 Diabetes · recruiting
- NCT06883344 — Automated Insulin for Management of Intrapartum Glycemia · NA · recruiting
Other Castilla-La Mancha Health Service trials
Trials by the same sponsor.
- NCT06466967 — Clinical Utility of Tight Objectives of Advanced Hybrid Closed-loop Systems Among Type 1 Diabetes Patients (TightT1AHCL) · completed
- NCT06214780 — Effect of Heatwaves on Glycemic Control in People With Type 1 Diabetes Treated With Artificial Pancreas · completed
- NCT06222775 — Multicomponent Intervention on Lifestyle, Anthropometric Measurements, Glycemic Control and Quality of Life in Patients · NA · unknown
- NCT05918484 — Usefulness of Continuous Glucose Monitoring in MODY Diagnosis · completed
- NCT05646017 — Effect of Heatwave Over Glycemic Control in Patients With T1D · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06834334 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Castilla-La Mancha Health Service
- Last refreshed: 19 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06834334.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing