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NCT06833723

Development of a Multi-omics Prediction Model for Immunotherapy Response in Triple-Negative Breast Cancer Subtypes

Active, enrolled Last updated 15 January 2026
What this trial tests

trial testing Retrospective Data Collection and Analysis in Breast Neoplasms in 1,000 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
17 April 2025
Primary endpoint
17 December 2025
17 November 2027

Quick facts

Lead sponsorHangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment1,000
Start date17 April 2025
Primary completion17 December 2025
Estimated completion17 November 2027
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences

Who can join

18 and older, female only, with Breast Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to collect clinical samples from breast cancer patients who have undergone or are expected to undergo immunotherapy at our institution. The samples, including fresh tissue from diagnostic punctures, residual tumor tissue post-surgery, blood samples, and imaging data, will be used to build a predictive model for immunotherapy efficacy. The research will employ proteomics, transcriptomics, metabolomics sequencing, imaging mass cytometry (IMC), and spatial transcriptomics to construct a multi-omics, multi-dimensional (temporal and spatial) model to predict the effectiveness of immunotherapy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Mapping the rapid growth of multi-omics in tumor immunotherapy: Bibliometric evidence of technology convergence and paradigm shifts.
    Dong H, Wang X, Zheng Y, Li J, et al · · 2025 · cited 5× · PMID 40275437 · DOI 10.1080/21645515.2025.2493539

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Other trials of Retrospective Data Collection and Analysis

Trials testing the same drug.

Other recruiting trials for Breast Neoplasms

Currently open trials in the same condition.

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Data sources for this page

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