NCT06828549: MOSAIC

MObile Support Adapted to Individual Contexts

ENROLLING BY INVITATION NA Last updated 5 March 2026

What this trial tests

NA trial testing MOSAIC in Type 2 Diabetes in 547 participants. Enrolling by invitation.

Timeline

21 March 2025

Primary endpoint
30 November 2028

30 November 2028

Quick facts

Lead sponsor	Vanderbilt University Medical Center
Phase	NA
Status	ENROLLING BY INVITATION
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	547
Start date	21 March 2025
Primary completion	30 November 2028
Estimated completion	30 November 2028
Sites	2 locations across United States

Drugs / interventions tested

• MOSAIC
• Print Materials

Conditions studied

• Type 2 Diabetes — all drugs for Type 2 Diabetes →

Sponsor

Vanderbilt University Medical Center

Who can join

Adults 18 to 75, any sex, with Type 2 Diabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This behavioral clinical trial evaluates an adaptively tailored, mobile phone-delivered intervention (MOSAIC) designed to support adults managing their type 2 diabetes. Adaptive means the intervention can change over time. Tailored means the intervention may be different for different participants. The main questions the study will aim to answer are:

1. Does the diabetes education and support delivered via the MOSAIC adaptive mobile phone-delivered intervention improve outcomes more than diabetes education and support delivered via print materials alone? This aim compares the study arms on outcomes such as glycemic management (hemoglobin A1c), diabetes distress, and psychosocial well-being. This aim also compares the study arms on intervention targets (mediators) including diabetes self-efficacy and self-care behaviors.
2. For whom does the MOSAIC adaptive tailoring approach improve outcomes more than the print materials alone? This aim examines how well the tailoring rules used for the MOSAIC intervention worked for different participants on the outcomes examined in the first aim.

Participants will enroll in a 16-month study with assessments every 4 months. Assessments include completion of an A1c test and a survey. For those assigned to MOSAIC, they will experience 12-months of mobile phone-delivered support with 3 opportunities for intervention tailoring.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.