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NCT06824636

Per Kilogram Versus Nitrogen Balance Methods for Daily Protein Requirement in Cancer Patients

Completed NA Last updated 13 February 2025
What this trial tests

NA trial testing a personalized diet plan was prepared according to the calculated requirements of each patient by two expert dietitians in Nitrogen Balance in 103 participants. Completed in 30 March 2020.

Timeline
1 September 2019
Primary endpoint
30 January 2020
30 March 2020

Quick facts

Lead sponsorIstanbul University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeprevention
Enrollment103
Start date1 September 2019
Primary completion30 January 2020
Estimated completion30 March 2020
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Istanbul University

Who can join

18 and older, any sex, with Nitrogen Balance or Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to compare the effects of two dietary protein supplementation methods (per kg \[PK\] vs nitrogen balance equation \[NBE\]) on nutritional status, muscle strength, lean body mass, physical performance, and dietary compliance in cancer patients. The main questions it aims to answer are: Does the PK method improve muscle strength and lean body mass more effectively than the NBE method? Which method better supports nutritional status and physical performance in cancer patients? Are there differences in dietary compliance between the two methods? Researchers will compare the PK method (1.2-1.5 g/kg/day protein) to the NBE method (protein requirements based on nitrogen balance) to evaluate their impact on these outcomes. Participants will: Follow a personalized diet plan based on either the PK or NBE method Attend follow-up visits at weeks 4 and 8 for assessments of BMI, muscle mass, muscle strength, gait speed, serum albumin, and CRP Engage in moderate aerobic exercise (brisk walking) for at least 30 minutes a day, 5 days a week

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

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